PORTFOLIO / Assistant Professor Marko Šestan DVM

Portfolio

Assistant Professor

Marko Šestan

DVM

Faculty of Medicine

Contact

Visibility

Education

01.10.2014. - 09.07.2018.

PhD

Doctoral study of Biomedicine

Faculty of Medicine, University of Rijeka

01.10.2006. - 07.12.2012.

DVM

Veterinary medicine

University of Zagreb, Faculty of veterinary medicine

01.09.2002. - 01.06.2006.

High school education

Science and mathematics

High school Lucijan Vranjanin

Work Experience

01.07.2023. -

Assistant professor

Assistant professor on Deportment for histology and embryology

Faculty of Medicine, University of Rijeka

01.03.2019. - 31.08.2022.

Post doc

EMBO fellowship

Champalimaud Research, Champalimaud Centre for the Unknown, Champalimaud Foundation, Lisbon, Portugal.

01.02.2018. - 30.06.2023.

Assistant, post-doc

PhD student on Department of histology and embryology

Faculty of Medicine, University of Rijeka

12.12.2013. - 31.01.2018.

PhD student

Project associate. Project title: „The role of pathogen driven inflammation of visceral adipose tissue in the development of diabetes mellitus type II“.

Faculty of Medicine, University of Rijeka

01.06.2013. - 02.12.2013.

Doctor of veterinary medicine

Veterinary medicine

Specialist veterinary practice for small animals Dr. Pezo

Awards and Honours

2020.

EMBO scholarship for post-doctoral training at Fundação Champalimaud, Champalimaud Research, Champalimaud Center for the Unknown, Lisbon, Portugal. Scholarship period: March 1, 2020. – 31.05.2023

10.2019.

Annual award of the Croatian Immunological Society for the best published scientific work during 2018

2019.

Award for best young scientist at University of Rijeka.

2019.

State award for scientific discovery.

10.2018.

Award of the Croatian Immunological Society for the best PhD in the period 2016-2018.

2018.

EFIS Travel Scholarship award for participation in the 5th European congress of immunology, Amsterdam, Netherlands.

2018.

First prize for oral presentation of scientific work at Annual Meeting of the Croatian Immunological Society 2018, Zadar, Croatia.

2018.

Award for best young scientist in School of Medicine, Rijeka, Croatia. Basic biomedicine.

15.10.2016.

7. Third prize for oral presentation of scientific work. Annual Meeting of the Croatian Immunological Society 2016, Ogulin, Croatia.

2015.

EFIS Travel Scholarship award for participation in the 4th European congress of immunology, Vienna, Austria.

11.11.2011.

Dean's Award for excellent success in the 5th year of studies in the academic year 2010/2011.

17.06.2011.

Rector's award for student work "Morphology and immunophenotype of lymphoma in dogs in the Republic of Croatia"

Membership of Professional Associations

2014. -

Croatian Immunological Society

2014. -

Croatian Laboratory Animal Scientific Association

Teaching

Courses

01.03.2024.

Osnove embriologije i teratologije

Sveučilišni prijediplomski studij Medicinsko laboratorijska dijagnostika

Medicinski fakultet Sveučilišta u Rijeci

voditelj

01.10.2023. -

Teratogenic factors of the environment

University undergraduate study of Environmental and Public Health

Faculty of Medicine, University or Rijeka

Course coordinator

01.10.2023. -

Basis of anatomy and histology

University undergraduate study of Environmental and Public Health

Faculty of Medicine, University or Rijeka

Course coordinator

01.10.2022. -

Anatomy and histology

University integrated undergraduate and graduate study of pharmacy

Faculty of Medicine, University or Rijeka

Associate

01.10.2020. -

Animal Models of Human Diseases

University integrated undergraduate and graduate study of Medicine on English

Faculty of Medicine, University or Rijeka

Associate

01.10.2020. -

Animal Models of Human Diseases

University integrated undergraduate and graduate study of Medicine

Faculty of Medicine, University or Rijeka

Associate

01.10.2018. -

Histology and embryology

University integrated undergraduate and graduate study of Medicine on English

Faculty of Medicine, University or Rijeka

Associate

01.10.2016. -

Cell therapy

Biotechnology in medicine

Department of biotechnology

Associate

01.01.2014. -

Histology and Embriology

University integrated undergraduate and graduate study of Dental Medicine

Faculty of Medicine, University of Rijeka

Associate

01.01.2014. -

Histology

Medical Laboratory Diagnostics

Faculty of Medicine, University of Rijeka

Associate

01.01.2014. -

Histology and Embriology

University integrated undergraduate and graduate study of Medicine

Faculty of Medicine, University of Rijeka

Associate

Theses Supervision

01.07.2024.

Imunološkim sustavom posredovana regulacija metabolizma aminokiselina tijekom virusnih infekcija

Martina Brnjić

Biotehnologija u medicini

Fakultet biotehnologije i razvoja lijekova, Sveučilište u Rijeci

01.09.2023.

The role of thyroid hormones in the immune control of cytomegalovirus infection

Ivan Modrić

Medical Studies in English

Faculty of Medicine, University of Rijeka

Professional Training and Development

14.02.2014.

Cours on the education and training of persons working with laboratory animals and animals used in the production of biological produts (Category 3)

Financing: 80

Research

Journal Articles

2025.

Neuronal-ILC2 interactions regulate pancreatic glucagon and glucose homeostasis.

Šestan M, Raposo B, Rendas M, Brea D, Pirzgalska R, Godinho I, Ribeiro H, Carvalho T, Wueest S, Konrad D, Veiga-Fernandes H.

Science

Q1

2024.

The immunology of sickness metabolism

Wensveen, F. M., Šestan, M. & Polić, B

Cellular & molecular immunology. - 1051-1065

Q1

2024.

An IFNγ-dependent immune-endocrine circuit lowers blood glucose to potentiate the innate antiviral immune response

Šestan, M., Mikašinović, S., Benić, A., Wueest, S., Dimitropoulos, C., Mladenić, K., Krapić, M., Hiršl, L., Glantzspiegel, Y., Rasteiro, A., Aliseychik, M., Cekinović Grbeša, Đ., Turk Wensveen, T., Babić, M., Gat-Viks, I., Veiga-Fernandes, H., Konrad, D., Wensveen, F. M. & Polić, B.

Nature immunology - 981-993.

Q1

29.09.2023.

NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis

Sonja Marinović, Maja Lenartić, Karlo Mladenić, Marko Šestan, Inga Kavazović, Ante Benić, Mia Krapić, Lukas Rindlisbacher, Maja Cokarić Brdov̌ak, Colin Sparano, Gioana Litscher, Tamara Turk Wensveen, Ivana Mikolašević, Dora Fǔkar Čupić, Lidija Bilić-Zulle, Aleksander Steinle, Ari Waisman, Adrian Hayday, Sonia Tugues, Burkhard Becher, Bojan Polić, Felix M Wensveen

Science Immunology - 87

https://www.science.org/doi/abs/10.1126/sciimmunol.add1599

Q1

2021.

Blood glucose regulation in context of infection,

Wensveen, F. M., Šestan, M., Turk Wensveen, T. & Polić, B.

Vitamins and Hormones - 117 253-318

Q1

2020.

DIFFERENCES IN ATTITUDES ON VACCINATION BETWEEN HEALTHCARE WORKERS AND GENERAL POPULATION IN THE REPUBLIC OF CROATIA

DINKO PUNTARIĆ, IVA ŠESTAN, MARKO ŠESTAN, INA STAŠEVIĆ, DARKO ROPAC

Akademija medicinskih znanosti Hrvatske - 74 337-344

13.06.2019.

‘Beauty and the beast’ in infection: How immune–endocrine interactions regulate systemic metabolism in the context of infection

Felix M. Wensveen, Marko Šestan, Tamara Turk Wensveen, Bojan Polić

Eur. J. Immunol. - 982-995

Q1

17.07.2018.

Virus-induced IFN-gamma causes insulin resistance in skeletal muscle and derails glycemic control in obesity

Šestan M, Marinović S, Kavazović I, Cekinović Đ, Wueest S, Turk Wensveen T, Brizić I, Jonjić S, Konrad D, Wensveen FM, Polić B

Immunity - 49 164-177

https://www.cell.com/immunity/abstract/S1074-7613(18)30241-3

Q1

2018

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

Jelenčić V, Šestan M, Kavazović I, Lenartić M, Marinović S, Holmes TD, Prchal-Murphy M, Lisnić B, Sexl V, Bryceson YT, Wensveen FM, Polić B

Nature immunology - 19 1083-1092

Q1

2015.

NK cells link obesity-induced adipose stress to inflammation and insulin resistance

Wensveen FM, Jelenčić V, Valentić S, Šestan M, Turk Wensveen T, Theurich S, Glasner A, Mendrila D, Štimac D, Wunderlich FT, Bruning JC, Mandelboim O, Polić B.

Nature immunology - 16 376-385

Q1

2015.

The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation

Wensveen FM, Valentić S, Šestan M, Turk Wensveen T, Polić B

European journal of immunology - 45 2446-2456

Q1

2015.

Interactions between adipose tissue and the immune system in health and malnutrition

Wensveen FM, Valentić S, Šestan M, Turk Wensveen T, Polić B.

Seminars in immunology - 27 322-333.

Q1

2015

Excision of Visceral Adipose Tissue from Live Mice (VATectomy)

Šestan M, Wensveen FM, Polić B

Bio-protocol - 5

Books

2024.

Ten Cateova Oralna histologija

prevoditelj

Antonio Nanci

Medicinska naklada

Bojan Polić

Medicinska naklada Zagreb

03.2023.

Junqueira Osnove histologije, udžbenik i atlas

Translator

Mescher, Anthony L.

Marija Ćurlin; Dinko Mitrečić

Naklada Slap

2021.

VITAMINS AND HORMONES Hormones, Regulators and Viruses Poglavlje: Blood glucose regulation in context of infection

Book chapter author

Wensveen, F. M., Šestan, M., Turk Wensveen, T., & Polić, B

GERALD LITWACK, PhD

Elsevier

2014.

Immune mechanisms in inflammation of visceral adipose tissue as a basis for the development of type 2 diabetes and its clinical complications; in "Obesity: a public health problem and a medical challenge""

Author

Felix M Wensveen, Vedrana Jelenčić, Tamara Turk Wensveen, Marko Šestan, Sonja Valentić, Sebastian Theurich, Ariella Glasner, Davor Mendrila, Davor Štimac, F. Thomas Wunderlich, Jens C Brüning, Ofer Mandelboim, Bojan Polić

HAZU, Zavod za kliničku i transplantacijsku imunologiju i molekularnu medicinu u Rijeci; Rijeka; 2014.

Daniel Rukavina

HAZU, Zavod za kliničku i transplantacijsku imunologiju i molekularnu medicinu u Rijeci Rijeka, Croatia

Invited Lectures

13.10.2024.

Immune-mediated control of glucose metabolism in health and disease

Marko Šestan

Sisak

Conference Presentations

03.09.2024.

An IFN-dependent immuneendocrine circuit lowers blood glucose to potentiate the innate anti-viral immune response

Šestan M, Mikašinović S, Benić A, Wueest S, Dimitropoulos C, Mladenić K, Krapić M, Hiršl L, Glantzspiegel Y, Rasteiro A, Aliseychik M, Cekinović Grbeša Đ, Turk Wensveen T, Babić M, Gat-Viks I, Veiga-Fernandes H, Konrad D, Wensveen FM, Polić B.

poster prezentacija

7th European Congress of Immunology Dublin, Irska

10.2023.

Ménage à trois: Neuro-endocrino-immune regulation of metabolic homeostasis.

Marko Šestan, Bruno Raposo, Miguel Rendas, David Brea, Roksana Pirzgalska, Inês Godinho, Hélder Ribeiro, Tânia Carvalho and Henrique Veiga-Fernandes

Oral presentation

EFIS-EJI South Eastern European Immunology School 2023 Trogir, Croatia

05.2023.

Ménage à trois: Neuro-endocrino-immune regulation of metabolic homeostasis.

Marko Šestan, Bruno Raposo, Miguel Rendas, David Brea, Roksana Pirzgalska, Inês Godinho, Hélder Ribeiro, Tânia Carvalho and Henrique Veiga-Fernandes

Poster presentation

5th International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism Crete, Greece

10.2022.

Ménage à trois: Neuro-endocrino-immune regulation of metabolic homeostasis.

Marko Šestan, Bruno Raposo, Miguel Rendas, David Brea, Roksana Pirzgalska, Inês Godinho, Hélder Ribeiro, Tânia Carvalho and Henrique Veiga-Fernandes

Oral presentation

Annual meeting of the Croatian Immunological society Sveti Martin na Muri, Croa

10.2021.

Ménage à trois: Neuro-endocrino-immune regulation of metabolic homeostasis.

Marko Šestan, Bruno Raposo, Miguel Rendas, David Brea, Roksana Pirzgalska, Inês Godinho, Hélder Ribeiro, Tânia Carvalho and Henrique Veiga-Fernandes

Oral presentation

Annual meeting of the Croatian Immunological society Online

10.2018.

Virally induced hypoglycaemia: good bad or bad bad?

Marko Šestan, Felix Wensveen, Bojan Polić

Oral presentation

Annual meeting of the Croatian Immunological society Zadar, Croatia

19.09.2015.

Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Felix M. Wensveen, Polić B

Poster presentation

18th FEBS Summer School on Immunology "Immune System: Genes, Receptors and Regulation" Rabac, Croatia

21.11.2014.- 22.11.2014.

Cytomegalovirus infection enhances development of diabetes mellitus type 2

Marko Šestan, Felix M Wensveen, Sonja Valentić, Bojan Polić

Poster presentation

2nd Waldthausen castle symposium Margaret Gladys Smith 60th anniversary of cytomegalovirus isolation Mainz, Germany.

17.10.2014. - 18.10. 2014

Cytomegalovirus infection enhances development of diabetes mellitus type 2 in obesity

Marko Šestan, Felix M Wensveen, Sonja Valentić, Bojan Polić

Oral and poster presentation

Annual meeting of the Croatian Immunological society Krk, Croatia

Virus-induced IFN-gamma causes insulin resistance in the skeletal muscle and derails glycemic control in obesity

Marko Šestan, Sonja Marinović, Inga Kavazović, Đurđica Cekinović, Stephan Wueest, Tamara Turk Wensveen, Ilija Brizić,Stipan Jonjić, Daniel Konrad, Felix M. Wensveen Bojan Polić

Poster presentation

5th European Congress of Immunology Amsterdam, Netherlands

06.-09.09.2018.

Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Felix M. Wensveen, Polić B

Poster presentation

4th European Congress of Immunology Vienna, Austria

21.-25.01.2018.

Virus-induced IFN-gamma causes insulin resistance in the skeletal muscle and derails glycemic control in obesity

Šestan M, Valentić S, Brizić I, Jonjić S, Wensveen FM, Polić B.

Poster presentation

Keystone Symposia; Organ crosstalk in obesity and NAFLD Keystone, USA

20.-21.10.2017.

Virus-induced IFNg causes insulin resistance in muscle and derails glycemic control in obesity

Šestan M, Valentić S, Kavazović I, Brizić I, Jonjić S, Wensveen FM, Polić B.

Oral and poster presentation

Annual meeting of the Croatian Immunological society Zagreb, Croatia

23.-30.09.2017.

Virus-induced IFNg causes insulin resistance in muscle and derails glycemic control in obesity

Šestan M, Valentić S, Brizić I, Jonjić S, Wensveen FM, Polić B.

Poster presentation

19th FEBS Summer School on Immunology "Immune System: Genes, Receptors and Regulation Hvar, Croatia

14.-15.10.2016.

Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Brizić I, Jonjić S, Wensveen FM, Polić B.

Oral and poster presentation

Annual meeting of the Croatian Immunological society Ogulin, Croatia

29.-30.09.2016.

Viral infections enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Brizić I, Jonjić S, Wensveen FM, Polić B.

Oral presentation

10th anniversary of the Center for Proteomics "Viral pathogenesis and immunity". Rijeka, Croatia

21.08.-26.08.2016.

Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Brizić I, Jonjić S, Wensveen FM, Polić B.

Oral presentation

16th International Congress of Immunology 2016 - ICI2016 Melbourne, Australia

07. - 14.05.2016.

Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Reichel J, Brizć I, Jonjic S, Wensveen FM, Polić B

Poster presentation

11th ENII EFIS EJI Summer School on Advanced Immunology Olbia, Italy

8.03. - 13.03.2015.

Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity

Šestan M, Valentić S, Wensveen FM, Polić B

Poster presentation

Spring School on Immunology 2015 DGFI Ettal, Germany

Organisation of Conferences and Symposia

10.2023.

EFIS-EJI South Eastern European Immunology School 2023

Trogir, Croatia Oral and poster presentation

05.2023.

5th International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism

Crete, Greece poster presentation

10.2022.

Annual meeting of the Croatian Immunological society

Sveti Martin na Muri, Croatia Oral presentation

10.2020.

Annual meeting of the Croatian Immunological society

Online Oral presentation

10.2018.

Annual meeting of the Croatian Immunological society

Zadar, Croatia Oral and poster presentation

02.09.2018. - 05.09.2018.

5th European Congress of Immunology

Amsterdam, Netherlands poster presentation

21.01.2018. - 25.01.2018.

Keystone Symposia; Organ crosstalk in obesity and NAFLD

Keystone, SAD poster presentation

20.10.2017. - 21.10.2017.

Annual meeting of the Croatian Immunological society

Zagreb, Croatia Oral and poster presentation

23.09.2017. - 30.09.2017.

19th FEBS Summer School on Immunology "Immune System: Genes, Receptors and Regulation"

Hvar, Croatia poster presentation

14.10.2016. - 15.10.2016.

19th FEBS Summer School on Immunology "Immune System: Genes, Receptors and Regulation"

Ogulin, Croatia Oral and poster presentation

29.09.2016. - 30.09.2016.

10th anniversary of the Center for Proteomics "Viral pathogenesis and immunity"

Rijeka, Croatia Oral presentation

21.08.2016. - 26.08.2016.

16th International Congress of Immunology 2016 - ICI2016

Melbourne, Australia Oral presentation

07.05.2016. - 14.05.2016.

1th ENII EFIS EJI Summer School on Advanced Immunology

Olbia, Italy poster presentation

12.09.2015. - 19.09.2015.

18th FEBS Summer School on Immunology "Immune System: Genes, Receptors and Regulation",

Rabac, Croatia poster presentation

06.09.2015. - 09.09.2015.

4th European Congress of Immunology

Vienna, Austria poster presentation

08.03.2015. - 13.03.2018.

Spring School on Immunology 2015 DGFI

Ettal,Germany poster presentation

26.10.2014.

EAGEN Course Obesity – metabolic and nutritional problem in Western and Eastern Europe

Opatija, Croatia -

18.10.2014.

Annual meeting of the Croatian Immunological society

Krk, Croatia Oral and poster presentation

27.09.2014.

The Interplay of Biomolecules, HDBMB 2014.

Zadar, Croatia

21.03.2014. -

Training on Preclinical testing opportunitiesin frame of the IPA SIIF-funded project “Becoming entrepreneurial: Knowledge transfer from the University of Rijeka Faculty of Medicine to the biotechnology business sector”

Rijeka, Croatia

06.12.2013. -

Training on Partnership Strategies in Developing Diagnostic Tools in frame of the IPA SIIF-funded project “Becoming entrepreneurial: Knowledge transfer from the University of Rijeka Faculty of Medicine to the biotechnology business sector“

Rijeka, Croatia

21.-22.11.2014.

2nd Waldthausen castle symposium Margaret Gladys Smith 60th anniversary of cytomegalovirus isolation

Mainz, Germany. poster presentation

Community Engagement

Outreach

14.05.2024.

Pint of Science

Predavanje

Caffe bar Tor

Media Appearances

12.03.2025.

Znanost sa potpisom

Hrvatska radio televizija

Zagreb

Administrative Roles

University Boards and Committees

01.01.2025.

član

Povjerenstvo za dobrobit životinja

01.04.2014. - 28.02.2019.

member

Faculty of Medicine, University of Rijeka/Animal Welfare Committee

Committees Outside the University

2014. - 2019.

member

Faculty of Medicine, University of Rijeka/Animal Welfare Committee

Projects

Research Projects

16.05.2024. - 30.09.2025.

"Za tango treba dvoje" - IMUNO-endoKRINA regulacija razina glukoze tijekom jakih, neletalnih virusnih infekcija

voditelj

Sveučilište u rijeci 7.392,95 Eura

18.12.2023. - 17.12.2027.

Uloga adiponektina u biologiji memorijskih CD8 T stanica

suradnik

HRZZ 199.083,18 Eura

07.04.2021. - 20.04.2022.

Neuro-endocrino-immune regulation of metabolic homeostasis

Project PI

UNIRI 49.375,67 KN

1.3.2021. - 28.2. 2023.

Ménage à trois: Neuro-endocrino-immune regulation of metabolic homeostasis

Project PI

Acteria 100.000,00 E

2021. - 2023.

Regulation of intestinal immunity by brain-derived signals.

Associate

FCT Projectos de investigaçao científica e desenvolvimento tecnológico 248.338,75 €

2018. - 2022.

The role of innate immune cells in the development of nonalcoholic steatohepatitis (NASH) and liver fibrosis

Associate

UNIRI 235.868,31

01.06.2017.-31.05.2021.

Immune mechanisms in the development of inflammation and metabolic syndrome in obesity

Associate

HRZZ 998.568,00 HRK

01.06.2015.-31.12.2016.

Mechanisms of innate immunity in the development of visceral adipose tissue inflammation and insulin resistance in obesity

Associate

ESF 1.960.612,15 KN

12.2.2013. - 01.01.2015.

„The role of pathogen-driven inflammation of visceral adipose tissue in the development of diabetes mellitus type II“

Associate, PhD student

UKF

2013. - 2017.

The role of innate immunity mechanisms in the development of chronic inflammation of visceral adipose tissue and type 2 diabetes mellitus

Associate

UNIRI 392.332,00 KN

01.01.2013. - 01.01.2015.

Fat Killers: The role of Natural Killer cells in the development of Diabetes Mellitus type 2

Associate

EFSD 100,000 EURA

Research Projects - Project Leader/Principal Investigato

PROJECTS OF YOUNG SCIENTISTS AND ARTISTS 2020

Research Projects - Project Member/Project Researcher

Project subsidies 2017 - young researchers
Project subsidies 2016 - young researchers