PORTFELJ / prof. dr. sc Milan Mesić

Portfelj

prof. dr. sc

Milan Mesić

Fakultet biotehnologije i razvoja lijekova

Zavod za molekularnu i sistemsku biomedicinu

Obrazovanje

1994.

doktor znanosti

kemija

Prirodoslovno matematički fakultet

1991.

magistar kemije

kemija

Prirodoslovno matematički fakultet

1988.

VSS profesor biologije i kemije

profesor biologije i kemije

Pedagoški fakultet Osijek

Radno iskustvo

2023.

Redoviti profesor u trajnom zvanju

Redoviti profesor u trajnom zvanju

Fakultet biotehnologije i razvoja lijekova

Znanstvena djelatnost

Znanstveni radovi

2023

Chemical proteomics approach for detection of potential off-targets associated with the EGFRi erlotinib

Kovačević, Tatjana; Nujić, Krunoslav; Mesić, Milan;

Book of Abstracts

2013

Conformational properties and chiral separation of dibenzo [b, f] thieno [3, 4-d]-fused oxepines and thiepines

Landek, Goran; Ozimec Landek, Ivana; Pešić, Dijana; Mesić, Milan; Šunjić, Vitomir;

Monatshefte für Chemie-Chemical Monthly - 144

Autorski indeks

Gabelica Marković, V; Mesić, M; AlihodŢić, S;

2023

Different chemical proteomic approaches to identify the targets of lapatinib

Kovačević, Tatjana; Nujić, Krunoslav; Cindrić, Mario; Dragojević, Snježana; Vinter, Adrijana; Hozić, Amela; Mesić, Milan;

Journal of Enzyme Inhibition and Medicinal Chemistry - 38

1994

Rearrangement of bicyclo [3.2. 0] heptyl precursors to the 7-norbornyl cation in the cryogenic SbF5 matrix

Mesić, Milan; Sunko, Dionis E; Vančik, Hrvoj;

Journal of the Chemical Society, Perkin Transactions 2

2011

Primjena znanstvenih rezultata u proizvodnji Kemija u tvrtki Galapagos istraživački centar doo

Gabelica Marković, V; Mesić, M; Alihodžić, S; Kovačević, K;

Kemija u industriji: Časopis kemičara i kemijskih inženjera Hrvatske - 60

Modifikacije 1-tiadibenzo [e, h] azulena u položaju 8: sinteza i protuupalno djelovanje

Ozimec Landek, Ivana; Mesić, Milan; Pešić, Dijana; Stanić, Barbara; Hrvačić, Boška; Merćep, Mladen;

2010

LANDEK IO* 1, PEŠIĆ D. 1, TROJKO R. 1, 2, BOGDANOVIĆ MD 1, 3

MERĆEP, M; MESIĆ, M;

HETEROCYCLES - 81

1998

C–H Hyperconjugation in α-chlorocarbocations

Mesić, Milan; Novak, Igor; Sunko, Dionis E; Vančik, Hrvoj;

Journal of the Chemical Society, Perkin Transactions 2

1998

Lyotropic Liquid Crystalline Phases from Symmetric Double-Tailed Surfactants: Sodium 1′-(6)-Undecylbenzenesulfonate, 1′-(7)-Tridecylbenzenesulfonate, and 1′-(8)-Pentadecylbenzenesulfonate in Water

Jalšenjak, Nenad; Mesić, Milan; Mihalić, Zlatko; Pavešić, Nasta; Pracaić, Suzana; Težak, Đurđica; Platz, Gerhard; Peukert, Susane; Ulbricht, Werner; Danino, Dganit;

Journal of colloid and interface science - 208

2006

Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma

Hrvačić, Boška; Bošnjak, Berislav; Tudja, Marijan; Mesić, Milan; Merćep, Mladen;

Pharmaceutical research - 23

1991

Reactivations of acetylcholinesterase inhibited by organophosphorus compounds. Imidazole derivatives. II

Mesić, M; Deljac, A; Deljac, V; Binenfeld, Z; Kilibarda, V; Maksimović, M; Kovačević, V;

Acta Pharm. Jugosl - 41

Opis wynalazku

Rupčić, M Modrić; Hutinec, A; Čikoš, A; Stanić, B; Mesić, M; Pešić, D; Merćep, M; Heterocycl, J;

2008

Measurement of malondialdehyde (MDA) level in rat plasma after simvastatin treatment using two different analytical methods

Lovrić, Jasna; Mesić, Milan; Macan, Marija; Koprivanac, Marijan; Kelava, Marta; Bradamante, Vlasta;

Periodicum biologorum - 110

2011

Synthesis and anti‐inflammatory activity of 8H‐1‐thia‐8‐aza‐dibenzo [e, h] azulenes

Ozimec Landek, Ivana; Pešić, Dijana; Merćep, Mladen; Stanić, Barbara; Mesić, Milan;

Journal of Heterocyclic Chemistry - 48

2011

Applying Research Results to Production Chemistry in the Galapagos Research Center Ltd., Zagreb

Gabelica Marković, V; Mesić, M; Alihodžić, S; Kovačević, K;

Kemija u industriji: Časopis kemičara i kemijskih inženjera Hrvatske - 60

1994

Reactivators of acetylcholinesterase inhibited by organophosphorus compounds. Imidazole derivatives

Mesić, M; Rončević, R; Radić, B; Fajdetić, A; Binenfeld, Z;

Acta Pharm - 44

2007

Synthesis of 2‐formyl‐1‐aza‐dibenzo [e, h] azulenes

Pešić, Dijana; Landek, Ivana Ozimec; Čikoš, Ana; Metelko, Biserka; Gabelica, Vesna; Stanić, Barbara; Merćep, Mladen; Mesić, Milan;

Journal of Heterocyclic Chemistry - 44

2D versus 3D cell culture platforms for screening antitumoral activity of novel chemical entities

Trzun, M; Paravić Radičević, A; Frka Borić, K; Jelić, D; Vujasinović, I; Mesić, M; Eraković Haber, V; Brajša, K;

2013

Synthesis and anti-inflammatory activity of novel furochromenes

Elenkov, Ivaylo Jivkov; Hrvačić, Boška; Marković, Stribor; Mesić, Milan; Čempuh Klonkay, Andreja; Lerman, Lidija; Filipović Sučić, Anita; Vujasinović, Ines; Bošnjak, Berislav; Brajša, Karmen;

Croatica Chemica Acta - 86

1996

Effects of Structure on the Reactivity of α-Hydroxydialkylnitrosamines in Aqueous Solutions1

Mesić, Milan; Revis, Cynthia; Fishbein, James C;

Journal of the American Chemical Society - 118

Differences in anticancer drug sensitivities in 3D and 2D cancer cell culture systems: model on ADAM10 novel anticancer drug target and biomarker

Trzun, M; Paravić Radičević, A; Frka Borić, K; Jelić, D; Vujasinović, I; Mesić, M; Eraković Haber, V; Brajša, K;

2018

Methods for arylethylation of amines and heteroarenes

Manallack, D; Prankerd, R; Yuriev, E; Oprea, T; Chalmers, D; Dong, H; Latka, R; Driver, T; Wekesa, F; Phadke, N;

SynOpen - 2

2001

Chemoenzymatic synthesis of all four cytoxazone stereoisomers

Hameršak, Zdenko; Ljubović, Edina; Merćep, Mladen; Mesić, Milan; Šunjić, Vitomir;

Synthesis - 2001

1997

Antidotal efficacy of quinuclidinium oximes against soman poisoning

Lucić, A; Radić, B; Peraica, M; Mesić, M; Primožič, I; Binenfeld, Z;

Archives of toxicology - 71

2006

Volatile constituents from flowers, leaves, bark and wood of Prunus mahaleb L.

Mastelić, Josip; Jerković, Igor; Mesić, Milan;

Flavour and fragrance journal - 21

2011

Determination of aqueous stability and degradation products of series of coumarin dimers

Dragojević, Snježana; Šunjić, Vitomir; Bencetić-Mihaljević, Vlatka; Ralić, Jovica; Mesić, Milan; Elenkov, Ivaylo Jivkov; Sučić, Anita Filipović; Klonkay, Andreja Čempuh; Lerman, Lidija; Ilijaš, Marina;

Journal of pharmaceutical and biomedical analysis - 54

1996

Failure to isolate the first N-nitrosiminium cation

Chahoua, Latifa; Mesić, Milan; Fishbein, James C;

The Journal of Organic Chemistry - 61

2019

Benzoxaboroles—Novel autotaxin inhibitors

Kraljić, Kristina; Jelić, Dubravko; Žiher, Dinko; Cvrtila, Adam; Dragojević, Snježana; Sinković, Verona; Mesić, Milan;

Molecules - 24

2013

Macrolactonolides: a novel class of anti-inflammatory compounds

Tomašković, Linda; Komac, Marijana; Stegić, Oresta Makaruha; Munić, Vesna; Ralić, Jovica; Stanić, Barbara; Banjanac, Mihailo; Marković, Stribor; Hrvačić, Boška; Paljetak, Hana Čipčić;

Bioorganic & medicinal chemistry - 21

2012

Dibenzo [b, f] oxepin‐10 (11H)‐one and Dibenzo [b, f] thiepin‐10 (11H)‐one as Useful Synthons in the Synthesis of Various Dibenzo [e, h] azulenes

Pešić, Dijana; Landek, Ivana Ozimec; Rupčić, Renata; Modrić, Marina; Džapo, Iva; Trojko, Rudolf; Merćep, Mladen; Mesić, Milan;

Journal of Heterocyclic Chemistry - 49

1993

Die Struktur des 7‐Norbornyl‐Kations und seine Umlagerung in das 2‐Norbornyl‐Kation

Sieber, Stefan; Schleyer, Paul von Ragné; Vančik, Hrvoj; Mesić, Milan; Sunko, Dionis E;

Angewandte Chemie - 105

2010

Novel tetracyclic imidazole derivatives: Synthesis, dynamic NMR study, and anti‐inflammatory evaluation

Rupčić, Renata; Modrić, Marina; Hutinec, Antun; Čikoš, Ana; Stanić, Barbara; Mesić, Milan; Pešić, Dijana; Merćep, Mladen;

Journal of Heterocyclic Chemistry - 47

2011

A conjugate of pyridine-4-aldoxime and atropine as a potential antidote against organophosphorus compounds poisoning.

Lovrić, Jasna; Berend, Suzana; Vrdoljak, Ana Lucić; Radić, Božica; Katalinić, Maja; Kovarik, Zrinka; Želježić, Davor; Kopjar, Nevenka; Rast, Slavko; Mesić, Milan;

Acta Biochimica Polonica - 58

1993

The Nature of the 7‐Norbornyl Cation and its Rearrangement into the 2‐Norbornyl Cation

Sieber, Stefan; von Ragué Schleyer, Paul; Vančik, Hrvoj; Mesić, Milan; Sunko, Dionis E;

Angewandte Chemie International Edition in English - 32

2000

Mechanisms of decomposition of α-hydroxydialkylnitrosamines in aqueous solution

Milan Mesic’,; Peuralahti, Jari; Blans, Patrick; Fishbein, James C;

Chemical Research in Toxicology - 13

2010

Synthesis of naphtho [2, 3-b]-and naphtho [1, 2-b]-fused thieno [2, 3-d][1] benzoxepins and thieno [2, 3-d][1] benzothiepins

Landek, Ivana Ozimec; Pesic, Dijana; Trojko, Rudolf; Bogdanovic, Maja Devcic; Mercep, Mladen; Mesic, Milan;

Heterocycles - 81

2018

An alternative synthesis of the non-small cell lung carcinoma drug afatinib

Kovacevic, Tatjana; Mesic, Milan; Avdagic, Amir; Zegarac, Miroslav;

Tetrahedron Letters - 59

2006

Synthesis of 1, 8‐Dioxa‐dibenzo [e, h] azulenes.

Pesic, Dijana; Landek, Ivana Ozimec; Mercep, Mladen; Mesic, Milan;

ChemInform - 37

1996

Imidazolium and quinuclidinium oximes as antidotes in soman poisoning

Lucić, Ana; Radić, Božica; Primožič, Ines; Rončevič, Renata; Mesić, Milan;

Toxicology Letters

2010

Novel spirotetracyclic zwitterionic dual H1/5-HT2A receptor antagonists for the treatment of sleep disorders

Gianotti, Massimo; Botta, Maurizio; Brough, Stephen; Carletti, Renzo; Castiglioni, Emiliano; Corti, Corrado; Dal-Cin, Michele; Delle Fratte, Sonia; Korajac, Denana; Lovric, Marija;

Journal of medicinal chemistry - 53

1997

Evidence for the Formation of α-Hydroxydialkylnitrosamines in the pH-Independent Solvolysis of α-(Acyloxy) dialkylnitrosamines

Chahoua, Latifa; Mesic, Milan; Revis, Cynthia L; Vigroux, Alain; Fishbein, James C;

The Journal of Organic Chemistry - 62

2006

Synthesis Of 1, 8‐dioxa‐dibenzo [e, h] azulenese

Pešić, Dijana; Landek, Ivana Ozimec; Merćaep, Mladen; Mesića, Milan;

Journal of Heterocyclic Chemistry - 43

2012

Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin

Perić, Mihaela; Fajdetić, Andrea; Rupčić, Renata; Alihodžić, Sulejman; Žiher, Dinko; Bukvić Krajačić, Mirjana; Smith, Kirsten S; Ivezić-Schönfeld, Zrinka; Padovan, Jasna; Landek, Goran;

Journal of medicinal chemistry - 55

2009

2, 8-Dithia-dibenzo [e, h] azulenes and their 8-oxa analogs. synthesis and anti-inflammatory activity

Landek, Ivana Ozimec; Pešic, Dijana; Novak, Predrag; Stanic, Barbara; Nujic, Krunoslav; Mercep, Mladen; Mesic, Milan;

Heterocycles - 78

2010

Bogdanović, 2 Mladen Merćep, 3 and Milan Mesić

Landek, Ivana Ozimec; Pešić, Dijana; Trojko, Rudolf; Devčić, Maja;

HETEROCYCLES - 81

2010

LANDEK IO* 1, PEŠIĆ D. 1, TROJKO R. 1, 2, BOGDANOVIĆ MD 1, 3

MERĆEP, M; MESIĆ, M;

HETEROCYCLES - 81

Modifikacije 1-tiadibenzo [e, h] azulena u položaju 8: sinteza i protuupalno djelovanje

Ozimec Landek, Ivana; Mesić, Milan; Pešić, Dijana; Stanić, Barbara; Hrvačić, Boška; Merćep, Mladen;

2011

Primjena znanstvenih rezultata u proizvodnji Kemija u tvrtki Galapagos istraživački centar doo

Gabelica Marković, V; Mesić, M; Alihodžić, S; Kovačević, K;

Kemija u industriji: Časopis kemičara i kemijskih inženjera Hrvatske - 60

1994

Rearrangement of bicyclo [3.2. 0] heptyl precursors to the 7-norbornyl cation in the cryogenic SbF5 matrix

Mesić, Milan; Sunko, Dionis E; Vančik, Hrvoj;

Journal of the Chemical Society, Perkin Transactions 2

2023

Different chemical proteomic approaches to identify the targets of lapatinib

Kovačević, Tatjana; Nujić, Krunoslav; Cindrić, Mario; Dragojević, Snježana; Vinter, Adrijana; Hozić, Amela; Mesić, Milan;

Journal of Enzyme Inhibition and Medicinal Chemistry - 38

Autorski indeks

Gabelica Marković, V; Mesić, M; AlihodŢić, S;

2013

Conformational properties and chiral separation of dibenzo [b, f] thieno [3, 4-d]-fused oxepines and thiepines

Landek, Goran; Ozimec Landek, Ivana; Pešić, Dijana; Mesić, Milan; Šunjić, Vitomir;

Monatshefte für Chemie-Chemical Monthly - 144

2023

Chemical proteomics approach for detection of potential off-targets associated with the EGFRi erlotinib

Kovačević, Tatjana; Nujić, Krunoslav; Mesić, Milan;

Book of Abstracts

Administrativna djelatnost

Rukovođenje u državnoj upravi

2021.

član

Upravni odbor HRZZ

Projekti