PORTFELJ / Prof. dr. sc. Ivana Munitić dr. med.; dr. sc.

Portfelj

Prof. dr. sc.

Ivana Munitić

dr. med.; dr. sc.

Fakultet biotehnologije i razvoja lijekova

Zavod za molekularnu i sistemsku biomedicinu

Kontakt

T 385 51 584 579

UNIRI e-mail

e-mail 1

PROSTORIJA Odjel za Biotehnologiju, Sveučilište u Rijeci, Radmile Matejčić, O-220

PROSTORIJA O-236-laboratorij, telefon: 385 51 584 582

Vidljivost

Obrazovanje

2004. - 2006.

Doktorat znanosti iz područja imunologije

Ph.D.

University René Descartes-Paris 5, Paris, France.

1991. - 1997.

Doktor medicine

Studij medicine

Medicinski Fakultet Sveučilišta u Zagrebu

Radno iskustvo

1.3.2024. -

Redoviti profesor

Fakultet biotehnologije i razvoja lijekova

2019. - 2022.

Predstojnica Zavoda za molekularnu i sistemsku medicinu

Odjel za biotehnologiju, Sveučilište u Rijeci

15.12.2018. -

Izvanredni profesor

Odjel za biotehnologiju, Sveučilište u Rijeci

2013. -

Docent; voditelj laboratorija

Docent na Odjelu za Biotehnologiju Sveučilišta u Rijeci. Voditelj Laboratorija za molekularnu imunologiju.

Odjela za biotehnologiju, Sveučilište u Rijeci

2009. - 2012.

Postdoktorand

Gostujući znanstvenik (research fellow), Laboratory of Immune Cell Biology.

National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

2005. - 2009.

Postdoktorand

Gostujući znanstvenik, INSERM U591- Différenciation thymique et physiologie des lymphocytes T.

Hôpital Necker, Paris, France.

2000. - 2004.

Postdoktorand

Gostujući znanstvenik (visiting fellow), Laboratory of Immune Cell Biology.

National Cancer Institute, National Institutes of Health. Bethesda, MD.USA.

1998. - 1999.

Znanstveni novak

Znanstveni novak na Katedri za Patofiziologiju.

Medicinski Fakultet, Sveučilišta u Zagrebu.

1997. - 1998.

Liječnički staž

Obavezni liječnički staž

Bolnica Merkur, Zagreb

Nagrade i priznanja

2005-2007.

Marie Curie Incoming Fellowship, European Union.

2000-2004.

Fogarty International Fellowship, USA.

1995-1997.

Rektorova nagrada, Sveučilišta u Zagrebu.

Članstva

2015. -

Hrvatsko društvo za neuroznanost

2014. -

Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB)

2014. -

American Association of Immunologists (AAI)

2013. -

European Federation of Immunological Societies (EFIS)

2013. -

Hrvatsko imunološko društvo (HID)

Nastavna djelatnost

Kolegiji

2017-sada

Neuroscience

Studij biotehnologije

Odjel za Biotehnologiju, Sveučilište u Rijeci

suradnik

2016-sada

Neuroimunologija

Studij Biotehnologije

Odjel za Biotehnologiju, Sveučilište u Rijeci

voditelj

2016-sada

Uvod u Istraživački rad

Studij Biotehnologije

Odjel za Biotehnologiju, Sveučilište u Rijeci

suradnik

2015-sada

Fiziologija i patofiziologija

Studij biotehnologije.

suradnik

2015-sada

Imunologija

Studij biotehnologije.

Odjel za Biotehnologiju, Sveučilište u Rijeci

voditelj

2015-sada

Metodologija znanstveno-istraživačkog rada

Doktorski studij «Medicinska kemija»

Odjel za Biotehnologiju, Sveučilište u Rijeci

voditelj

2014-sada

Capstone Course in Pathophysiology

University of Minnesota Summer School zajedno s Odjelom za Biotehnologiju

Odjel za Biotehnologiju, Sveučilište u Rijeci

suradnik

2013-2016

Uvod u istraživački rad

Studij biotehnologije.

Odjel za Biotehnologiju, Sveučilište u Rijeci

voditelj

2013-2015

Imunoterapija

Studij biotehnologije.

Odjel za Biotehnologiju, Sveučilište u Rijeci

voditelj

1998-1999.

Patofiziologija

Studij medicine

Medicinski Fakultet Sveučilišta u Zagrebu.

suradnik

Mentor u završnim radovima

26.10.2023.

Validating a new cell model for an interactome mapping of ALS- linked optineurin mutation Q398X

Antonija Braut

Medicinska kemija

Sveučilište u Rijeci, Odjel za biotehnologiju

26.10.2023.

The role of optineurin in phagocytosis of fibrillar amyloid  in bone marrow-derived macrophages and dendritic cells

Bruno Komušanac

Biotehnologija u medicini

Sveučilište u Rijeci, Odjel za biotehnologiju

18.07.2023.

Analysis of potential neuroinflammatory pathology in the spinal cords of mice with optineurin insufficiency

Marta Kolarić

Biotehnologija i istraživanje lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

24.10.2022.

mRNA cjepiva protiv bolesti COVID-19

Andrea Montan:

Biotehnologija i istraživanje lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

28.09.2022.

Assessing optineurin protein features and pathogenicity of its variants in amyotrophic lateral sclerosis and glaucoma by bioinformatic analysis

Toni Franjkić

Biotehnologija u medicini

Sveučilište u Rijeci (Odjel za biotehnologiju)

27.09.2022.

Interaction of optineurin and TDP-43 in cell models of amyotrophic lateral sclerosis

2022. Marija Marošević:

Biotehnologija u medicini

Sveučilište u Rijeci, Odjel za biotehnologiju

27.09.2022.

The role of optineurin in the process of phagocytosis

Katarina Bulić

Biotehnologija u medicini

Sveučilište u Rijeci, Odjel za biotehnologiju

19.09.2022.

Eksperimentalni modeli multiple skleroze

Adrian Perhart:

Biotehnologija i istraživanje lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

20.09.2021.

Pasivna imunoterapija za COVID-19 infekcije

Klara Erceg

Biotehnologija i istraživanje lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

19.10.2020.

Optineurin u neurodegenerativnim bolestima

Lorena Šimunić

Biotehnologija i istraživanje lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

29.09.2020.

Utjecaj nedostatka optineurina u autofagiji induciranoj s IFN-β

Rozalija Šajn

Biotehnologija u medicini

Sveučilište u Rijeci (Odjel za biotehnologiju)

27.08.2020.

The cell-specific role of optineurin in TLR4- and ER stress-mediated activation of the NF-κB pathway

Josip Peradinović

Biotehnologija u medicini

Sveučilište u Rijeci (Odjel za biotehnologiju)

30.07.2020.

Imunoterapija T-stanicama transduciranim kimeričnim antigenim receptorima

Marija Marošević

Studij biotehnologije i istraživanja lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

17.09.2019.

Uloga optineurina u autofagiji potaknutoj unutarstaničnim bakterijama te interferonom beta

Valentina Štimac

Biotehnologija u medicini

Sveučilište u Rijeci, Odjel za biotehnologiju

16.09.2019.

Neuroinflammatory processes in amyotrophic lateral sclerosis (ALS) - genetic evidence and therapies

Erika Radović

Studij biotehnologije i istraživanja lijekova)

University of Rijeka (Department of Biotechnology)

16.09.2019.

In vitro characterization of TNF-mediated programmed death in cells with optineurin deficiency

Karla Dubaić

Biotehnologija u medicini

Sveučilište u Rijeci (Odjel za biotehnologiju)

10.09.2019.

The role of B cells in the pathogenesis and therapy of multiple sclerosis

Katarina Bulić

Studij biotehnologije i istraživanja lijekova

Sveučilište u Rijeci (Odjel za biotehnologiju)

2017-2018

Uloga optineurina u infekciji herpes simpleks virusa 1

Ana Vidulić

Diplomski studij "Biotehnologija u medicini"; opaska: komentorstvo s doc. I. Jurakom

Odjel za biotehnologiju

2017-2018

Characterizing the role of optineurin in inflammatory signaling in microglial and neuronal cell lines

Matea Rob

Diplomski studij "Biotehnologija u medicini"

Odjel za biotehnologiju

2017-2018

Analiza autofagije u staničnoj liniji Neuro 2a s CRISPR/Cas9 posredovanom delecijom optineurina

Nikolina Prtenjača

Diplomski studij "Biotehnologija u medicini"

Odjel za biotehnologiju

2017-2018

Uloga IFN-ß u patogenezi i liječenju multiple skleroze

Karlo Mladenić

Preddiplomski sveučilišni studij "Biotehnologija i istraživanje lijekova"

Odjel za biotehnologiju

2017-2018

IMMUNOTHERAPEUTIC APPROACHES FOR ALZHEIMERS DISEASE

Klara Krpina

Preddiplomski sveučilišni studij "Biotehnologija i istraživanje lijekova"

Odjel za biotehnologiju

2017-2018

Characterization of neuroinflammation in neuronal and microglial cell lines lacking optineurin

Alicia Pliego Mendieta

Erasmus dolazak s Universidad Europea Madrid

Odjel za biotenologiju i Universidad Europea Madrid

2016-2017

ANALYSIS OF T FOLLICULAR HELPER CELL DEVELOPMENT IN THE CONTEXT OF VIRAL INFECTIONS

Vendi Šinkovec

Diplomski studij "Biotehnologija u medicini"; opaska: komentorstvo s dr. M. Kuka (San Raffalle Hospital, Milano)

Odjel za biotehnologiju

2015-2016

Istraživanje uloge optineurina prilikom procesa autofagije

Tereza Ljutić

Diplomski studij "Medicinska kemija"

Odjel za biotenologiju

2014-2015

Uloga optineurina u NF-?B i TBK1 signalnim putevima

Mia Jakopović

Diplomski studij "Biotehnologija u medicini"

Odjel za biotehnologiju

2014-2015

Uloga mikroglije u amiotrofičnoj lateralnoj sklerozi

Marina Rumora

Preddiplomski sveučilišni studij "Biotehnologija i istraživanje lijekova"

Odjel za biotehnologiju

Osobni razvoj

2015. -

Advanced BD FACSAriaTM III Operator Training

2008. -

In Vivo Non-Linear Microscopy - Foundations and Applications.

2004. -

Vaccines.

2002. -

Molecular and Cellular Mechanisms of Immunity II.

2000. -

Molecular and Cellular Mechanisms of Immunity.

1998. -

Summer School on Molecular Medicine.

1990. -

Advanced English Course.

Znanstvena djelatnost

Znanstveni radovi

2021.

Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact

De Marchi, Fabiola ; Munitic, Ivana ; Amedei, Amedeo ; Berry, James D. ; Feldman, Eva L. ; Aronica, Eleonora ; Nardo, Giovanni ; Van Weehaeghe, Donatienne ; Niccolai, Elena ; Prtenjaca, Nikolina ; Sakowski, Stacey A. ; Bendotti, Caterina ; Mazzini, Letizia

Neuroscience & Biobehavioral Reviews - 127 958-978

https://pubmed.ncbi.nlm.nih.gov/34153344/

Q1

2020.

Optineurin dysfunction in amyotrophic lateral sclerosis: why so puzzling?

NIKOLINA PRTENJAČA, MARIN DOMINOVIĆ, JOSIP PERADINOVIĆ, ROZALIJA ŠAJN, ANDREA MARKOVINOVIĆ, IVANA MUNITIĆ

Periodicum Biologorum - 121–122 23–34

https://hrcak.srce.hr/ojs/index.php/periodicum_biologorum/article/view/10627

Q3

2020.

Immunity in amyotrophic lateral sclerosis: blurred lines between excessive inflammation and inefficient immune responses

Louis-Charles Béland, Andrea Markovinovic, Hrvoje Jakovac, Fabiola De Marchi, Ervina Bilic, Letizia Mazzini, Jasna Kriz, and Ivana Munitic

Brain Communications - 2 fcaa124

https://academic.oup.com/braincomms/article/2/2/fcaa124/5892251?login=true

Q1

11.12.2019.

Editorial: The Role of Optineurin in Immunity and Immune-Mediated Diseases.

Smith AM, Buss F, Munitic, I.

Frontiers in Immunology - 10 2803

Q1

03.06.2019.

Attenuation of ALS progression during pregnancy-lessons to be learned or just a coincidence

Hancevic, M Bilic, H Sitas, B Pavlisa, G Borovecki, F Munitic, I Bilic, E

Neurological Sciences - 40 1275-1278.

https://www.ncbi.nlm.nih.gov/pubmed/30746559

Q2

20.05.2019.

Glia in ALS and spinal cord injury: common therapeutic targets

Ban, Jelena; Mladinic, Miranda; Sámano, Cynthia; Munitic, Ivana

Croatian medical journal - 60 109-120

https://www.ncbi.nlm.nih.gov/pubmed/31044582

Q2

12.07.2018.

Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-ß Responses.

Markovinovic A, Ljutic T, Béland LC, and Munitic I.

Neuroscience - 388 139-151

Q1

2017.

Optineurin in amyotrophic lateral sclerosis: Multifunctional adaptor protein at the crossroads of different neuroprotective mechanisms

Markovinović, Andrea ; Cimbro, Raffaello ; Ljutić, Tereza ; Križ, Jasna ; Rogelj, Boris ; Munitić, Ivana

Progress in neurobiology - 154 1-20

https://www.ncbi.nlm.nih.gov/pubmed/28456633

06.04.2017.

Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents.

Malatesti, N Munitic, I Jurak, I

Biophysical Reviews - 9 149-168

https://www.ncbi.nlm.nih.gov/pubmed/28510089

2017.

Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents

Malatesti, Nela ; Munitic, Ivana ; Jurak, Igor

Biophysical Reviews - 9 149-168

https://link.springer.com/article/10.1007/s12551-017-0257-7

01.09.2016.

Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing.

Pourcelot M, Zemirli N, Silva Da Costa L, Loyant R, Garcin D, Vitour D, Munitic I, Vazquez A, and Arnoult, D.

BMC Biology - 14 69

https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0292-z

Q1

2016.

The TBK1-binding domain of optineurin promotes type I interferon responses

Meena, Netra Pal ; Zhu, Guozhi ; Mittelstadt, Paul R. ; Giardino Torchia, Maria Letizia ; Pourcelot, Marie ; Arnoult, Damien ; Ashwell, Jonathan D. ; Munitić, Ivana

FEBS letters - 590 1498-1508

http://www.ncbi.nlm.nih.gov/pubmed/27086836

2015.

Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis

Li, Caiyi C. ; Munitić, Ivana ; Mittelstadt, Paul R. ; Castro, Ehydel ; Ashwell, Jonathan D.

PLoS biology - 13 1-16

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002269

2015.

c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8+ memory T-cell survival

MLG Torchia, I Munitic, E Castro, J Herz, DB McGavern, JD Ashwell

European Journal of Immunology

http://www.ncbi.nlm.nih.gov/pubmed/?term=c-IAP+ubiquitin+protein+ligase+activity+is+required+for+4-1BB+signaling+and+CD8%2B+memory+T-cell+survival.

Q1

2012.

CD70 Deficiency Impairs Effector CD8 T Cell Generation and Viral Clearance but Is Dispensable for the Recall Response to Lymphocytic Choriomeningitis Virus

Munitić, Ivana ; Kuka, M. ; Allam, A. ; Scoville, J. P. ; Ashwell, J.D.

Journal of immunology - 190 1169-1179

http://www.jimmunol.org/content/190/3/1169.abstract?sid=986a0595-f024-496b-a83d-c65be95581da

2013.

CD70 Is Downregulated by Interaction with CD27

Kuka, M. ; Munitić, Ivana ; Giardino Torchia, M.L. ; Ashwell, J.D.

Journal of immunology - 191 2282-2289

http://www.jimmunol.org/content/191/5/2282.abstract?sid=986a0595-f024-496b-a83d-c65be95581da

2013.

Optineurin Insufficiency Impairs IRF3 but not NF-?B Activation in Immune Cells.

Munitic, I*, Giardino Torchia, ML, Meena NP, Zhu G, Li CC, Ashwell, JD*. * Corresponding authors.

The Journal of Immunology, 1301696 (Epub Nov 15)

http://www.jimmunol.org/content/early/2013/11/15/jimmunol.1301696.abstract

Q1

2012.

Identi?cation and characterization of polyclonal ?ß-T cells with dendritic cell properties.

Kuka, M, Munitic, I, Ashwell, JD.

Nature Communications. - 1223

http://www.ncbi.nlm.nih.gov/pubmed/23187623

Q1

2010.

Gamma(c) deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors.

Decaluwe, H. ; Taillardet, M. ; Corcuff, E. ; Munitić, Ivana ; Law, H. K. W. ; Rocha, B. ; Riviere, Y. ; Di Santo, J.P.

Proceedings of the National Academy of Sciences of the United States of America - 107 9311-9316

http://www.ncbi.nlm.nih.gov/pubmed/20439728

2010.

Transcriptional Regulation during CD8 T-Cell Immune Responses

Munitic, Ivana ; Evaristo, César ; Sung, Hsueh Cheng ; Rocha, Benedita

Advances in Experimental Medicine and Biology - 11-27

http://www.ncbi.nlm.nih.gov/pubmed/20795537

2009.

The CD8+ memory T-cell state of readiness is actively maintained and reversible

Allam, A. ; Conze, D.B. ; Giardino Torchia, M.L. ; Munitić, Ivana ; Yagita, H. ; Sowell, R. T. ; Marzo, A.L. ; Ashwell, J.D.

Blood - 114 2121-2130

http://www.ncbi.nlm.nih.gov/pubmed/19617575

2009.

Epitope Specificity and Relative Clonal Abundance Do Not Affect CD8 Differentiation Patterns during Lymphocytic Choriomeningitis Virus Infection

Munitić, Ivana ; Decaluwe, H. ; Evaristo, C. ; Lemos, S. ; Wlodarczyk, M. ; Worth, A. ; Le Bon, A. ; Selin, L.K. ; Riviere, Y. ; Di Santo, J.P. ; Borrow, P. ; Rocha, B.

Journal of virology - 83 11795-11807

http://www.ncbi.nlm.nih.gov/pubmed/19726518

2007.

CD8 single-cell gene co-expression reveals three different effector types present at distinct phases of the immune response.

Peixoto A, Evaristo C, Munitic I, Monteiro M, Charbit A, Rocha B. Veiga-Fernandes H.

Journal Experimental Medicine - 204 1193-205.

http://www.ncbi.nlm.nih.gov/pubmed/17485515

Q1

2005.

T Cells in G1 Provide a Memory-Like Response to Secondary Stimulation

Munitić, Ivana ; Ryan, P.E. ; Ashwell, J.D.

Journal of immunology - 174 4010-4018

http://www.ncbi.nlm.nih.gov/pubmed/15778358

2004.

Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis

Munitić, Ivana ; Williams, J.A. ; Yang, Y. ; Dong, B. ; Lucas, P.J. ; El Kassar, N. ; Gress, R.E. ; Ashwell, J.D.

Blood - 104 4165-4172

http://www.ncbi.nlm.nih.gov/pubmed/15328149

2002.

Regulation of constitutive T cell receptor internalization by the ? chain.

Oro U*, Munitic I*, Chacko G, Karpova T, McNally J, Ashwell JD. *These authors contributed equally to this manuscript.

Journal of Immunology - 169 6269-78.

http://www.ncbi.nlm.nih.gov/pubmed/12444133

Q1

2007.

CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

Peixoto, António ; Evaristo, César ; Munitić, Ivana ; Monteiro, Marta ; Charbit, Alain ; Rocha, Benedita ; Veiga-Fernandes, Henrique

The Journal of experimental medicine - 204 1193-1205

2002.

Regulation of constitutive TCR internalization by the zeta-chain

D'Oro, U. ; Munitić, Ivana ; Chacko, G. ; Karpova, T. ; McNally, J. ; Ashwell, J.D.

Journal of immunology - 169 6269-6278

2013.

Optineurin Insufficiency Impairs IRF3 but Not NF-kappaB Activation in Immune Cells

Munitić, Ivana ; Giardino Torchia, M.L. ; Meena, N. P. ; Zhu, G. ; Li, C.C. ; Ashwell, J.D.

Journal of immunology - 191 6231-6240

2012.

Identification and characterization of polyclonal αβ-T cells with dendritic cell properties

Kuka, Mirela ; Munitić, Ivana ; Ashwell, Jonathan D.

Nature Communications - 3 11

2015.

c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8+memory T-cell survival

Giardino Torchia, Maria Letizia ; Munitić, Ivana ; Castro, Ehydel ; Herz, Jasmin ; McGavern, Dorian B. ; Ashwell, Jonathan D.

European journal of immunology - 45 2672-2682

2016.

The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

Pourcelot, Marie ; Zemirli, Naima ; Silva Da Costa, Leandro ; Loyant, Roxane ; Garcin, Dominique ; Vitour, Damien ; Munitić, Ivana ; Vazquez, Aimé ; Arnoult, Damien

Bmc biology - 14 18

2018.

Optineurin Insufficiency Disbalances Proinflammatory and Anti- inflammatory Factors by Reducing Microglial IFN-β Responses

Markovinovic, Andrea ; Ljutic, Tereza ; Béland, Louis-Charles ; Munitic, Ivana

Neuroscience - 388 139-151

2019.

Glia in Amyotrophic Lateral Sclerosis and Spinal Cord Injury: Common Therapeutic Targets

Ban, Jelena ; Mladinic, Miranda ; Sámano, Cynthia ; Munitic, Ivana

Croatian medical journal - 60 109-120

2019.

Učinak piridilporfirina na mitohondrije

Janković, Patrizia

- 69

2019.

Attenuation of ALS progression during pregnancy— lessons to be learned or just a coincidence?

Hančević, Mirea ; Bilić, Hrvoje ; Sitaš, Barbara ; Pavliša, Gordana ; Borovečki, Fran ; Munitić, Ivana ; Bilić, Ervina

Neurological sciences - 40 1275-1278

2019.

Editorial: The Role of Optineurin in Immunity and Immune-Mediated Diseases

Smith, Andrew M. ; Buss, Folma ; Munitic, Ivana

Frontiers in Immunology - 10 3

2020.

Immunity in amyotrophic lateral sclerosis: blurred lines between excessive inflammation and inefficient immune responses

Béland, Louis-Charles ; Markovinovic, Andrea ; Jakovac, Hrvoje ; De Marchi, Fabiola ; Bilic, Ervina ; Mazzini, Letizia ; Kriz, Jasna ; Munitic, Ivana

Brain Communications - 2 1-26

2020.

Optineurin Dysfunction in Amyotrophic Lateral Sclerosis: Why So Puzzling?

Prtenjaca, Nikolina ; Dominovic, Marin ; Peradinovic, Josip ; Šajn, Rozalija ; Markovinovic, Andrea ; Munitic, Ivana

Periodicum biologorum - 121-122 23-34

2019.

The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public

van der Spek, Rick A.A. ; van Rheenen, Wouter ; Pulit, Sara L. ; Kenna, Kevin P. ; van den Berg, Leonard H. ; Veldink, Jan H. ; on behalf of the Project MinE ALS Sequencing Consortium

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration - 20 432-440

Znanstvene knjige

2019

Dijagnostika i liječenje bolesti motoričkih neurona

autor poglavlja u priručniku

Munitić Ivana i Miholović Vesna

Uloga imunosnog sustava u nastanku i progresiji amiotrofične lateralne skleroze

Ervina Bilić

Pozvana predavanja

27.09.2019.

Optineurin Dysfunction in Amyotrophic Lateral Sclerosis (HDBMB Crossroads in Life Sciences)

Munitic I

Lovran, Croatia.

01.06.2019.

Optineurin Dysfunction in Neurodegeneration (Mind & Brain)

Munitic I

Pula, Croatia.

11.05.2019.

Immunity in Amyotrophic Lateral Sclerosis (International Conference on Neurological Disorders and Neurorestoration)

Munitic I

Dubrovnik, Croatia

05.10.2018.

Imunologija u ALS-u: pogled unatrag i unaprijed; Simpozije Dileme u neurologiji 2018

I. Munitić

Poreč

10.05.2018.

Cijepljenje: znanstvene i etičke dimenzije; Filozofski fakultet Sveučilišta u Rijeci

I. Munitić

Rijeka

03.05.2018.

Neuroimmunology of ALS (4th Croatian Neuroimmunological Congress with international participation)

Munitic I

Opatija, Hrvatska

02.02.2018.

Razvoj novih životinjskih modela za istraživanje amiotrofične lateralne skleroze; Godišnja skupština Hrvatskog društva za znanost o laboratorijskim životinjama (CroLASA),.

I. Munitić

Institut Ruđer Bošković, Zagreb

17.10.2017.

Animal Models of Amyotrophic Lateral Sclerosis; Croatian National Academy of Sciences and Arts 1st Rijeka Forum on Neurodegenerative Diseases, Rijeka,Croatia.

I. Munitić

Rijeka

19.09.2017.

Elucidating the role of optineurin in amyotrophic lateral sclerosis; Laval University, CERVO Brain, Research Centre Quebec City, Canada.

I. Munitić

Quebec City, Canada

16.09.2017.

Characterization of the role of optineurin in neurodegeneration, 13th Symposium of the André-Delambre Foundation, Montreal, Canada.

I. Munitić

Montreal, Canada

12.05.2017.

Molecular characterization of mouse optineurin insufficiency models; Regional meeting of clinicians and basic scientists that work on ALS, Ljubljana, Slovenia.

I. Munitić

Ljubljana

25.04.2017.

Istraživanje uloge optineurina u neuroprotekciji, Rijeka, travanj 2017, Predstavljanje uspostavnog istraživačkog projekta Hrvatske zaklade za znanost (HRZZ).

Ivana Munitić

Medicinski fakultet, Rijeka

04.07.2016.

Symposium: Translation of Basic Immunology and Neuroscience Tools to Therapies: Where are We Now?; Croatian Academy for Sciences and Arts and Department of Biotechnology. Talk title: Animal models for elucidating the role of adaptor protein optineurin during inflammation.

Ivana Munitić

Odjel za biotehnologiju, Rijeka.

2016.

Iskustva i izazovi istraživača u biomedicini

Ivana Munitić

Filozofski fakultet Sveučilišta u Rijeci

14.10.2014.

Tribina HAZU, KBC – HLZ Podružnica Rijeka: "NOVIJA POSTIGNUĆA U IMUNOLOGIJI I HEMATOLOGIJI" Naslov predavanja: Nove funkcije dendritičkih stanica.

Ivana Munitić

Rijeka, Hrvatska.

01.09.2014.

10th Symposium of the André-Delambre Foundation, Amyotrophic Lateral Sclerosis: Causes and Therapeutic Perspectives. Naslov predavanja: A Mouse Model of Optineurin Insufficiency

Ivana Munitić

Montreal, Canada.

Kongresna priopćenja

2017

Characterization of the role of optineurin in neuroinflammation.

Andrea Markovinović, Tereza Ljutić, Milojević i Ivana Munitić

poster

Atypical dementias: from diagnosis to emerging therapies Trst, Italija.

2017

Neurohistopathological characterization of an optineurin insufficiency mouse model.

Hrvoje Jakovac, Andrea Markovinovic and Ivana Munitic

poster

Congress of Croatian Physiological Society and Regional Congress of the Physiological Societies Dubrovnik, Croatia

2017

Characterization of the role of optineurin in neurodegeneration.

Andrea Markovinović, Tereza Ljutić, Milojević i Ivana Munitić

poster

Young Neuroscientists Meeting (YMN) Zagreb, Croatia

2017

Characterization of neurodegeneration in an optineurin insufficiency mouse model.

Hrvoje Jakovac, Andrea Markovinovic and Ivana Munitic

poster

Annual Meeting Of The Croatian Immunological Society With EFIS On Tour Zagreb, Croatia

2017

Molecular characterization of mouse optineurin insufficiency models.

Andrea Markovinović, Tereza Ljutić i Ivana Munitić

poster

European Network for the Cure for ALS (ENCALS) meeting Ljubljana, Slovenija.

2017

Characterization of the optineurin insufficiency mouse model.

Tereza Ljutić, Andrea Markovinović, Sai Sampath Thammisetty, Jasna Križ, Ivana Munitić.

poster

Scientific poster day of CERVO Institute. Quebec city, Canada.

2016

An optineurin insufficiency model of ALS.

Munitic I, Markovinovic A, and Ashwell JD.

usmena prezentacija

ENCALS (European Network for the Cure of ALS) meeting Milano, Italy

2016.

An optineurin insufficiency model of ALS.

Munitic I, Markovinovic A, and Ashwell JD.

odabrano usmeno izlaganje

ENCALS (European Network for the Cure of ALS) meeting. Milano, Italy.

2015.

An optineurin insufficiency model as a potential tool for elucidating the pathogenesis of amyotrophic lateral sclerosis.

Markovinović A, Barukčić A, Jakopović M, Šinkovec V, Jakovac H, Grabušić K, Ashwell JD, and Munitić I.

poster

Croatian Society for Neuroscience meeting. Split, Croatia.

2015.

Endogenous glucocorticoids suppress dendritic cell-derived IL-12 and prevent death in LPS-induced sepsis, Selected Oral presentation.

Munitic I, Li CC, Mittelstadt PR, Castro E, and Ashwell JD.

odabrano usmeno izlaganje

4th European Congress of Immunology. Vienna, Austria.

2015.

Optineurin is dispensable for LPS- and Salmonella typhimurium-induced autophagy.

Munitic I, Giardino Torchia ML, and Ashwell JD.

poster

American Associations of Immunologists Annual Meeting. New Orleans, USA.

2014.

Optineurin is a Positive Regulator of IFN-ß.

Munitic I, Giardino Torchia ML, Meena NP, and Ashwell JD.

odabrano usmeno izlaganje

Annual meeting of the Croatian Imunological Society. Krk, Croatia.

2013.

A Mouse Model of Optineurin Insufficiency Exhibits Impaired Signaling via IRF3 but not NF-?B Activation Pathway.

Munitic I, Giardino Torchia ML, Meena NP, and Ashwell JD.

poster

4th Croatian Neuroscience Congres. Zagreb, Croatia.

2013.

Optineurin is Indispensible for Signaling via IRF3 but not NF-?B Activation Pathway.

Munitic I, Giardino Torchia ML, Meena NP, and Ashwell JD.

poster

2nd Meeting on Middle-European Societies for Immunology and Allergology. Opatija, Croatia.

Mentorstvo doktorandima

2020. - 2023.

Neuroimmunity in neurodegeneration

Josip Peradinović Doktorat

Medicinska kemija

Odjel za biotehnologiju, Sveučilište u Rijeci

01.03.2019. -

Crosstalk of TDP-43 and optineurin

Nikolina Prtenjača Doktorat

Medicinska kemija

Odjel za biotehnologiju, Sveučilište u Rijeci

20.08.2016. -

Establishing human peripheral blood optineurin deficiency models and evaluating their inflammatory profiles as a potential disease biomarkers

Raffaello Cimbro Doktorat

Medicinska kemija

Datum obrane: predviđeno vrijeme: u 2019 ili 2020

2015. - 2019.

Evaluacija neuroinflamacije u mišjem modelu insuficijencije optineurina

Andrea Markovinović Doktorat

Medicinska kemija

Datum obrane: predviđeni datum: prosinac 2018

Znanstveni skupovi

07.05.2018. - 07.05.2018.

2nd Meeting Of Basic Researchers And Clinicians Working On ALS (SLO/HR)

Odjel za biotehnologiju, Rijeka organizator

30.06.2016. -

International symposium for young neuroscience researchers: 20th Young Neuroscientists Meeting.

Odjel za biotehnologiju, Rijeka, Croatia. ko-organizator (glavni organizator Miranda Mladinić Pejatović)

4-5 srpnja 2016

Simpozij u organizaciji HAZU i Odjela za biotehnologiju (iz projekta voditeljice projekta, I. Munitić): TRANSLATION OF BASIC IMMUNOLOGY AND NEUROSCIENCE TOOLS TO THERAPIES:Where Are We Now?

Rijeka suorganizator (član znanstvenog odbora i predsjednik organizacijskog odbora)

Uredništva časopisa

2017-2018

Gostujući urednik za časopis Frontiers in Immunology; tema: The Role of Optineurin in Immunity and Immune-Mediated Diseases.

https://www.frontiersin.org/research-topics/6554/the-role-of-optineurin-in-immunity-and-immune-mediated-diseases

Recenzije

2017

Recenzent programa cjeloživotnog učenja (Sveučilište u Rijeci)

2016-2018

HRZZ recenzent

Javno djelovanje

Popularizacija znanosti

15.11.2019.

Organizacija skupa za popularizaciju znanosti i kritičkog mišljenja

STEM: Danas za sutra 2

Sveučilište u Rijeci

22.10.2018.

Organizacija skupa za popularizaciju znanosti i kritičkog mišljenja

STEM područje - danas za sutra

Sveučilište u Rijeci

09.10.2018.

Cijepljenje - najučinkovitija obrana protiv zaraznih bolesti

Opatija Coffeehouse debates

Opatija, Hotel Continental

2018.

Predavanje: Cijepljenje - znanstvene dimenzije

Dani Filozofskog fakulteta; tribina: Cijepljenje - znanstvene i etičke dimenzije

Filozofski fakultet Sveučilišta u Rijeci

2018.

Predavanje: Cijepljenje - najučinkovitija obrana protiv zaraznih bolesti

Baltazar na Gradini

Trsatska Gradina

2018.

Organizacija Otvorenog dana; Igrokaz: Tko je jači: Imuni sustav ili virusi?

Otvoreni dan odjela za biotehnologiju

Odjel za biotehnologiju, Sveučilište u Rijeci

2017.

Igrokaz: Tko je jači: Imuni sustav ili virusi?

Otvoreni dan odjela za biotehnologiju

Odjel za biotehnologiju, Sveučilište u Rijeci

2016.

Plenarno predavanje: Imuni nadzor mozga, te Otvorena vrata laboratorija

Otvoreni dan odjela za biotehnologiju

Odjel za biotehnologiju, Sveučilište u Rijeci

2015.

Predavanje: Mikroglija i ALS, te demonstracija: Određivanje krvnih grupa

Otvoreni dan odjela za biotehnologiju

Odjel za biotehnologiju, Sveučilište u Rijeci

Intervjui

23.02.2020.

Požrtvovni i kreativni znanstvenici: Upoznajte riječki tim Odjela za biotehenologiju

Novi list

Rijeka

02.08.2019.

?????????? ??????????????Odnos imunosnog sustava i mozga: ljubav ili mržnja??????????????? ?? ???????????? ???????????? ?????? ???????????????????????? ?????????????????? ?????????????? ?? ???????????? ???????????? ?????? ??????????????

Novi list; prilog Vox academiae

Novinski članci

11.10.2018.

Cijepljenje je dragulj prevencije zaraznih bolesti

Novi list

Opatija

Projekti

Znanstveni projekti

01.10.2018. - 30.09.2022.

Controlling neurodegeneration by modulating the crosstalk between inflammation and proteinopathy

voditelj

HRZZ 1.000.000, 00 kn

u izradi

2014. - 2017.

Elucidating the Role of Optineurin in Neuroprotection.

voditelj

Hrvatska Zaklada za Znanost 1,000,000 kn

http://www.optineurin-neuroimmunology.uniri.hr

Projekti u znanosti - Voditelj projekta

STIMULATIVNE POTPORE 2021
STIMULATIVNE POTPORE 2020
STIMULATIVNE POTPORE 2019
UNIRI PROJEKTI 2018
STIMULATIVNE POTPORE 2018
Potpore 2014/2016

Projekti u znanosti - Suradnik na projektu

UNIRI PROJEKTI 2018
Potpore 2017 - Mladi istraživači