10.05.2007. - 10.06.2013.

postdoktorand

Brigham and Women's Hospital, Harvard Medical School, Boston, SAD

01.09.2003. - 30.03.2007.

Dr. sc.

Prirodne znanosti

Fakultet kemije i farmacije, Julius-Maximilians Sveučilište u Wuerzburgu, Njemačka

01.09.1994. - 30.03.2000.

Diplomirani inženjer medicinske biokemije

Medicinska biokemija

Farmaceutsko-biokemijski fakultet, Sveučilište u Zagrebu

2019-

Izvanredni profesor

Istraživanje molekularnih mehanizama razvoja i funkcije trombocita; nastavna aktivnost (kolegiji "Opća fiziolgija i patofiziologija", "Stanična i molekularna biologija", "Biologija matičnih stanica", "Tkivno inženjerstvo")

Odjel za biotehnologiju, Sveučilište u Rijeci

2013-2019

Docent

Istraživanje molekularnih mehanizama razvoja trombocita; nastavna aktivnost (kolegij "Biologija matičnih stanica")

Odjel za biotehnologiju, Sveučilište u Rijeci

01.05.2007. - 01.06.2013.

Poslijedoktorand

Istraživanje uloge citoskeleta u razvoju megakariocita i trombocita, u laboratoriju prof. John H. Hartwig-a

Brigham and Women's Hospital, Harvard Medical School, Boston, SAD

2004. - 30.03.2007.

Doktorand

Doktorski studij, istraživanje signalnih puteva (ROS, cAMP, cGMP) u funkciji trombocita, mentori prof. Ulrich Walter i dr. Stepan Gambaryan

Institut für Klinische Biochemie und Pathobiochemie, Julius-Maximilians Sveučilište u Würzburgu, Njemačka

01.02.2001. - 31.12.2003.

Znanstveni novak

Istraživanje povezanosti određenih polimorfizama sa bolestima krvožilja (association studies) pod mentorstvom prof. Elizabete Topić

Klinički zavod za kemiju, KB "Sestre milosrdnice", Zagreb

01.05.2000. - 2001.

Stažist-volonter

Odrađivanje obaveznog radnog staža medicinske biokemije i laboratorijske hematologije, državni ispit položen u prosincu 2001.

Klinički zavod za kemiju, KB "Sestre milosrdnice", Zagreb

1999. -

Diplomant

Izrada diplomskog rada o učinku ohratoksina A na apoptozu i citoskelet bubrežnih staničnih linija, mentor prof. Karmele Barišić

Zavod za medicinsku biokemiju, Farmaceutsko-biokemisjki fakultet, Sveučilište u Zagrebu

15.11.2023.

Državna nagrada za znanost, područje biomedicine i zdravstva

07.09.2017.

PhD student Ivana Bertović - Award for the best oral presentation 1st Italian-UK Platelet Meeting, Bath, UK, 7-8. September 2017

23.09.2016.

PhD student Ivana Bertović - Scientific Award for Poster Presentation, 3rd European Platelet Network Conference (EUPLAN) 2016

2014.

NEWFELPRO fellowship (Marie Curie FP7-PEOPLE-2011-COFUND) (2 godine)

01.12.2010.

American Society of Hematology Travel Award

01.04.2001.

CEEPUS stipendija, Odjel za biokemiju, Fakultet farmacije, Karlovo sveučilište, Hradec Kralove, Republika Češka (2 mj)

01.03.1999.

CEEPUS stipendija, Institut za kliničku kemiju, Pečuh, Mađarska (1 mj)

1999.

Rektorova nagrada

1997.

Stipendija Sveučilišta u Zagrebu (1 godina)

1995.

Stipendija grada Zadra (5 godina)

3.2023.

član izvršnog odbora HDBMB

2018. -

American Society of Hematology (ASH)

2015. -

Biochemical Society

2014. -

European Association of Hematology (EHA)

2007. - 2010.

International Society on Thrombosis and Haemostasis (ISTH)

2002. -

Hrvatsko društvo biokemije i molekularne biologije (HDBMB)

01.10.2022.

Stanična i molekularna biologija

Prediplomski studij, Biotehnologija i istraživanje lijekova

Fakultet biotehnologije i razvoja lijekova

voditelj

1.10.2021. -

Opća fiziologija i patofiziologija

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju Sveučilišta u Rijeci

suradnik

1.10.2021.

Stanična i molekularna biologija

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju Sveučilišta u Rijeci

suvoditelj

01.10.2020. - 01.09.2021.

Stanična i molekularna biologija

Biotehnologija i istraživanje lijekova, I. g. prediplomski studij

Odjel za biotehnologiju

suradnik

01.10.2020. -

Tkivno inženjerstvo

Biotehnologija u medicini, I. g. diplomski studij

Odjel za biotehnologiju

ko-voditelj

01.10.2020. -

Biology of stem cells

Biotechnology for the Life Sciences; Medicinal chemistry, I.g. master programme

Odjel za biotehnologiju

voditelj

01.10.2019.

Farmakologija

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju, Svečilište u Rijeci

suradnik

12.06.2017. -

Uvod u znanstveni rad

Doktorski studij Medicinska kemija

Odjel za biotehnologiju

suradnik

01.10.2015. - 30.09.2021.

Opća fiziologija i patofiziologija

Biotehnologija i istraživanje lijekova; II. g. prediplomski studij

Odjel za biotehnologiju

voditelj

2014. - 01.09.2019.

Imunologija

Biotehnologija i istraživanje lijekova, III. g. prediplomski studij

Odjel za biotehnologiju

suradnik

2013. - 30.09.2020.

Biologija matičnih stanica

Biotehnologija i istraživanje lijekova, III. g. prediplomski studij

Odjel za biotehnologiju

voditelj

2013. -

Uvod u istraživački rad

Biotehnologija u medicini; Istraživanje i razvoj lijekova; Medicinska kemija, II. g. diplomski studij

Odjel za biotehnologiju

suradnik

26.09.2023.

The effect of PIKfyve and PI4KIIIβ inhibitors on platelet spreading

Korina Švorinić

Biotehnologija u medicini

Sveučilište u Rijeci Odjel za biotehnologiju

26.09.2023.

Učinak farmakološke inhibicije PI4KIIa i PI4KIIIb na citoskelet trombocita

Klaudia Liker

Biotehnologija u medicini

Sveučilište u Rijeci Odjel za biotehnologiju

18.07.2023.

Platelets and sepsis: literature analysis of differential gene expression of thrombospondin 1 and ADARs

Dejana Vujnović

Biotehnologij i istraživanje lijekova

Sveučilište u Rijeci Odjel za biotehnologiju

23.09.2022.

Analiza PI3P-vežućih proteina s FYVE domenom u transkriptomu i proteomu trombocita

Laura Barešić

Biotehnologij i istraživanje lijekova

Sveučilište u Rijeci Odjel za biotehnologiju

08.09.2022.

Analiza sortirajućih neksina u transkriptomu i proteomu trombocita

Sara Patačko

Biotehnologij i istraživanje lijekova

Sveučilište u Rijeci Odjel za biotehnologiju

15.07.2022.

Control of Platelet Glycoprotein Ib-IX and Integrin αIIbβ3 Receptor Trafficking

Lydia Knight

OptiLife

Sveučilište u Rijeci Odjel za biotehnologiju

20.09.2021.

Hematološki poremećaji uzrokovani ribosomopatijama

Korina Švorinić

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju Sveučilišta u Rijeci

28.07.2021.

Platelets – cells with many functions

Karla Soldatić

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju Sveučilišta u Rijeci

13.01.2020. - 25.09.2020.

The effect of phosphoinositol-4-kinase inhibition on spreading in human platelets

Iris Đurić

Biotehnologija u medicini

Odjel za biotehnologiju, Sveučilište u Rijeci

13.01.2020. - 17.07.2020.

Comparison of different FYVE domains and anti-PI3P antibody for monitoring the localization of PI3P in BALB 3T3 cells

Tea Bruketa

Biotehnologija u medicini

Odjel za biotehnologiju, Sveučilište u Rijeci

04.02.2019. - 10.09.2020.

Karakterizacija i kloniranje SNX9 fuzioniranog sa zelenim fluorescentnim proteinom u staničnoj liniji DAMI i HEK293

Eni Tomović

Biotehnologija u medicini

Odjel za biotehnologiju, Sveučiište u Rijeci

03.09.2018. - 15.07.2018.

Characterization of SACM1L phosphatase and PI4P in Dami cell line and primary megakaryocytes

Ana Bura

Biotehnologija u medicini

Odjel za biotehnologiju

02.04.2018. - 15.07.2019.

Analiza broja jezgrica u primarnim mišjim megakariocitima

Rozalija Šajn

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju

02.04.2018. - 12.07.2019.

Analiza LC3-II kao markera autofagije u različitim razvojnim stadijima megakariocita

Tea Bruketa

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju

02.10.2017. - 10.07.2017.

Analiza fosfoinozitidnih fosfataza u transkriptomu i proteomu ljudskih i mišjih trombocita

Martina Nenadić

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju

03.10.2016. - 28.09.2017.

Analiza ranih i kasnih endosoma u razvojnim fazama mišjih megakariocita

Roberta Kurelić

Istraživanje i razvoj lijekova

Odjel za biotehnologiju

03.10.2016. - 27.09.2017.

Matične stanice kao izvor megakariocita i trombocita

Roberta Padavić

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju

03.10.2016. - 07.09.2017.

Novi potencijalni interakcijski partneri: PI3P i protein kinaza A

Andrea Mihalić

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju

01.02.2016. - 26.09.2016.

Kloniranje, mutageneza i karakterizacija fosfatidilinozitol 3-monofosfat vezujućih domena u HEK293T i primarnim megakakriocitima

Paola Paškvan

Biotehnologija u medicini

Odjel za biotehnologiju

01.10.2015. - 22.09.2016.

Molekularni mehanizmi nastajanja trombocita

Iris Car

Istraživanje i razvoj lijekova

Odjel za biotehnologiju

01.10.2015. - 22.09.2016.

Uloga fosfoinozitida u membranskom unutarstaničnom prometu

Ana Bura

Istraživanje i razvoj lijekova

Odjel za biotehnologiju

28.09.2015. -

Ekspresija i funkcija Vps34 u nastanku protrombocita

Marija Banović

Biotehnologija u medicini

Odjel za biotehnologiju

14.07.2015. -

Regulacija prometa receptora filaminom A

Marta Ursić

Biotehnologija i istraživanje lijekova

Odjel za biotehnologiju

01.02.2014. - 01.06.2014.

Uloga filamina A u lokalizaciji trombopoetinskog receptora u primarnim mišjim megakariocitima

Romina Sabo

Istraživanje i razvoj lijekova

Odjel za biotehnologiju

7-9. svibnja 2014

Biotehnologija, farmacija

Fakultet biomedicinskih znanosti, Universidad Europea Madrid, Španjolska

suradnik

2023.

A Plethora of Functions Condensed into Tiny Phospholipids: The Story of PI4P and PI(4,5)P2

Bura A, Čabrijan S, Đurić I, Bruketa T, Jurak Begonja A

Cells. - 12(10) doi.org/10.3390/cells12101411

https://www.mdpi.com/2073-4409/12/10/1411

Q1

2023.

The intracellular and plasma membrane pools of PI4P control megakaryocyte maturation and proplatelet formation

Bura, Ana; Čabrijan, Sara; Bertović, Ivana; Begonja, Antonija Jurak

Research and Practice in Thrombosis and Haemostasis

https://www.sciencedirect.com/science/article/pii/S2475037923001425

Q1

2023.

Photodynamic Inhibition of Herpes Simplex Virus 1 Infection by Tricationic Amphiphilic Porphyrin with a Long Alkyl Chain

Jurak, Igor ; Cokarić Brdovčak, Maja ; Djaković, Lara ; Bertović, Ivana ; Knežević, Klaudia ; Lončarić, Martin ; Jurak Begonja, Antonija ; Malatesti, Nela

Pharmaceutics - 15 15

https://www.mdpi.com/1999-4923/15/3/956

Q1

2022.

Oculocerebrorenal syndrome of Lowe protein controls cytoskeletal reorganisation during human platelet spreading

Bura, Ana ; de Matteis, Maria Antonietta ; Bender, Markus ; Swinkels, Maurice ; Versluis, Jurjen ; Jansen, A. J. Gerard ; Jurak Begonja, Antonija

British Journal of Haematology - 1-13

https://onlinelibrary.wiley.com/share/author/4IIW5U4JDVXDPDCFWDAN?target=10.1111/bjh.18478

Q1

2022.

Early Endosomal Vps34-Derived Phosphatidylinositol-3-Phosphate Is Indispensable for the Biogenesis of the Endosomal Recycling Compartment

Marcelić, Marina ; Mahmutefendić Lučin, Hana ; Jurak Begonja, Antonija ; Blagojević Zagorac, Gordana ; Lučin, Pero

Cells - 11 30

Q1

2022.

Early Endosomal GTPase Rab5 Regulates GPIb Trafficking and Platelet Production In Vitro

Bertović, Ivana ; Kurelić, Roberta ; Mahmutefendić Lučin, Hana ; Jurak Begonja, Antonija

Arteriosclerosis, thrombosis, and vascular biology - 17

https://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.121.316552

Q1

2021.

Imaging of Intracellular and Plasma Membrane Pools of PI(4,5)P2 and PI4P in Human Platelets

Bura, Ana ; Jurak Begonja, Antonija

Life - 11 20

Q2

2021.

Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes.

Bertović, Ivana ; Bura, Ana ; Jurak Begonja, Antonija

Platelets - 12 1-13

https://www.tandfonline.com/doi/full/10.1080/09537104.2021.2007869?tab=permissions&scroll=top

Q1

2021.

Response of platelets to silver nanoparticles designed with different surface functionalization

Milić, Marija ; Cvetić, Željko ; Bendelja, Krešo ; Vuković, Barbara ; Galić, Emerik ; Ćurlin, Marija ; Dobrošević, Blaženka ; Jurak Begonja, Antonija ; Vinković Vrček, Ivana

Journal of inorganic biochemistry - 224 9

https://www.sciencedirect.com/science/article/pii/S0162013421002129?via%3Dihub

Q2

2021.

Proteomics: A Tool to Study Platelet Function

Shevchuk, Olga ; Begonja, Antonija Jurak Begonja ; Gambaryan, Stepan ; Totzeck, Matthias ; Rassaf, Tienush ; Huber, Tobias B. ; Greinacher, Andreas ; Renne, Thomas ; Sickmann, Albert

International journal of molecular sciences - 22 25

https://www.mdpi.com/1422-0067/22/9/4776

Q1

13.02.2020.

Vps34 derived phosphatidylinositol 3-monophosphate modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes.

Bertovic I, Kurelic R, Milosevic I, Bender M, Krauss M, Haucke V, Jurak Begonja A.

J Thrombosis Haemostasis

https://onlinelibrary.wiley.com/doi/abs/10.1111/jth.14764?af=R

Q1 WOS

15.10.2019.

Developmental differences in platelet inhibition response to PGE1

Veronica Palma-Barqueros, Jose Miguel Torregrosa, Eva Caparrós-Pérez, Nerea Mota, Natalia Bohdan, María del Carmen Llanos, Antonija Jurak Begonja, Martha Sola-Visner, Vicente Vicente, Raul Teruel-Montoya, José Rivera, Francisca Ferrer Marin

Neonatology - 29 1-9

Q1 Q2

2018

Regulacija megakariopoeze i trombopoeze.

Bertović I, Jurak Begonja A.

Bilten KroHema - 10 31-33

28.06.2017.

Isolation of F. novicida-containing phagosome from infected human monocyte derived macrophages.

Marecic V, Shevchuk O, Ozanic M, Mihelcic M, Steinert M, Jurak Begonja A, Abu Kwaik Y, Santic M.

Frontiers in Cellular and Infection Microbiology.

Q1 WOS

2015.

Molecular mechanisms of megakaryocyte and platelet development.

Begonja AJ

RAD Medical Sciences, journal of Croatian Academy of Sciences and Arts. - 42 35-47

2015.

CXCL12/SDF-1 Stimulates Megakaryocyte ß-1,4-Galactosyltransferase 1 Activity to Enhance Platelet Production in Vivo.

Giannini S, Adelman M, Jurak Begonja A, Hoffmeister K

The FASEB Journal - 29 719-22

http://www.fasebj.org/content/29/1_Supplement/719.22.short

Q1

2015.

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

Jurak Begonja A, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H.

Blood - Blood. 2015 Apr 2. pii: blood-2014-07-587600. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25838348

Q1 WOS Exc

2015.

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.

Grozovsky, Renata; Jurak Begonja, Antonija; Liu, Kaifeng; Visner, Gary; Falet, Herve; Hartwig, John H; Hoffmeister, Karin M

Nature Medicine - 21 47-54.

http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.3770.html

Q1 WOS Exc

2012.

High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)–mediated inhibition of platelet production

Thon, Jonathan N; Devine, Matthew T; Begonja, Antonija Jurak; Tibbitts, Jay; Italiano, Joseph E;

Blood - 120 1975-1984

Q1 WOS Exc

2012.

Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis

Begonja, Antonija Jurak; Gambaryan, Stepan; Schulze, Harald; Patel-Hett, Sunita; Italiano Jr, Joseph E; Hartwig, John H; Walter, Ulrich;

Experimental Hematology

Q1 WOS

2012.

Microtubule and cortical forces determine platelet size during vascular platelet production

Thon, Jonathan N; Macleod, Hannah; Begonja, Antonija Jurak; Zhu, Jie; Lee, Kun-Chun; Mogilner, Alex; Hartwig, John H; Italiano Jr, Joseph E;

Nature Communications - 3 852

Q1 WOS

2011.

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

Patel-Hett, Sunita; Wang, Hongbei; Begonja, Antonija J; Thon, Jonathan N; Alden, Eva C; Wandersee, Nancy J; An, Xiuli; Mohandas, Narla; Hartwig, John H; Italiano, Joseph E;

Blood - 118 1641-1652

Q1 WOS Exc

2011.

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

Begonja, Antonija Jurak; Hoffmeister, Karin M; Hartwig, John H; Falet, Hervé;

Blood - 118 2285-2295

Q1 WOS Exc

2010.

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

Falet, Hervé; Pollitt, Alice Y; Begonja, Antonija Jurak; Weber, Sarah E; Duerschmied, Daniel; Wagner, Denisa D; Watson, Steve P; Hartwig, John H;

The Journal of experimental medicine - 207 1967-1979

Q1 WOS

2009.

Phosphatidylserine surface expression and integrin ?IIbß3 activity on thrombin/convulxin stimulated platelets/particles of different sizes

Rukoyatkina, Natalia; Begonja, Antonija J; Geiger, Jörg; Eigenthaler, Martin; Walter, Ulrich; Gambaryan, Stepan;

British journal of haematology - 144 591-602

Q1 WOS

2007.

Thrombin stimulation of p38 MAP kinase in human platelets is mediated by ADP and thromboxane A2 and inhibited by cGMP/cGMP-dependent protein kinase

Begonja, Antonija Jurak; Geiger, Jörg; Rukoyatkina, Natalia; Rauchfuss, Steffen; Gambaryan, Stepan; Walter, Ulrich;

Blood - 109 616-618

Q1 WOS Exc

2006.

Phosphoproteomics of human platelets: A quest for novel activation pathways

Zahedi, René P; Begonja, Antonija J; Gambaryan, Stepan; Sickmann, Albert;

Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics - 1764 1963-1976

Q1 WOS

2006.

Platelet regulation by NO/cGMP signaling and NAD (P) H oxidase-generated ROS

Begonja, Antonija J; Teichmann, Lino; Geiger, Jörg; Gambaryan, Stepan; Walter, Ulrich;

Blood Cells, Molecules, and Diseases - 36 166-170

Q1 WOS

2005.

Platelet NAD (P) H-oxidase–generated ROS production regulates ?IIbß3-integrin activation independent of the NO/cGMP pathway

Begonja, Antonija Jurak; Gambaryan, Stepan; Geiger, Jörg; Aktas, Barsom; Pozgajova, Miroslava; Nieswandt, Bernhard; Walter, Ulrich;

Blood - 106 2757

Q1 WOS

2004.

Soluble adhesion molecules in acute ischemic stroke

Šimundić, Ana-Maria; Bašić, Vanja; Topić, Elizabeta; Demarin, Vida; Vrkić, Nada; Kunović, Branka; Štefanović, Mario; Begonja, Antonija

Clinical & investigative medicine (0147-958X) 27 (2004), 2; 86-92 - 27 86-92

Q1 WOS

2004.

Potent inhibition of human platelets by cGMP analogs independent of cGMP-dependent protein kinase

Gambaryan, Stepan; Geiger, Jörg; Schwarz, Ulrike R; Butt, Elke; Begonja, Antonija; Obergfell, Achim; Walter, Ulrich;

Blood - 103 2593-2600

Q1 WOS Exc

2003.

Croatian population data for the C677T polymorphism in methylenetetrahydrofolate reductase: frequencies in healthy and atherosclerotic study groups

Žuntar, Irena; Topić, Elizabeta; Vukosavić, Đuro; Vuković, Vlasta; Demarin, Vida; Begonja, Antonija; Antoljak, Nataša; Šimundić, Ana Maria

Clinica chimica acta (0009-8981) 335 (2003); 95-100 - 335 95-100

Q2 WOS

2002.

PCR-SSCP genotipizacija polimorfizma 4G/5G inhibitora-1 aktivatora plazminogena.

Begonja, Antonija; Šimundić, Ana-Maria; Štefanović, Mario; Topić, Elizabeta;

Biochem Med - 12 1-5

2023.

A Plethora of Functions Condensed into Tiny Phospholipids: The Story of PI4P and PI(4,5)P2

Bura, Ana ; Čabrijan, Sara ; Đurić, Iris ; Bruketa, Tea ; Jurak Begonja, Antonija

Cells - 12 1-21

25.05.2023.

Bleeding tendency in Lowe syndrome: OCRL controls cytoskeletal rearrangements during platelet adhesion.

Begonja AJ.

Lowe Syndrome Research Meeting 2023. TIGEM, Pozzuoli, Italija

https://www.lowetrust.com/lowe-symposium/

08.03.2023.

The Role of Phosphoinositides PI3P and PI4P in Platelet Production

Jurak Begonja A

Gordon Research Conference "Cell Biology of Megakaryocytes and Platelets", Barga, Italija

https://www.grc.org/cell-biology-of-megakaryocytes-and-platelets-conference/2023/

06.03.2023.

The GRC Power Hour - on diversity and inclusion in the scientific workplace.

Jurak Begonja A, Falet H

Gordon Research Conference "Cell Biology of Megakaryocytes and Platelets", Barga, Italija

https://www.grc.org/cell-biology-of-megakaryocytes-and-platelets-conference/2023/

01.10.2020.

Novel molecular mechanisms of thrombopoiesis.

Begonja AJ.

8th Croatian congress of hematologists. Online.

25.11.2019.

Tiny lipids in the big cells: The role of PI3P in megakaryocyte development and platelet production.

Begonja AJ.

St. Cloud State University, Department of Biology

03.09.2018.

Vesicular trafficking in megakaryopoiesis and platelet production: the role of PI3P and late endosomes/lysosomes

Begonja AJ.

FEBS 3+ konferncija "From Molecules to Living Systems", Siofok, Mađarska

15.05.2018.

Presentation of Career Path and Croatian Science Foundation Installation grant #2400: “The role of phosphoinositides in platelet formation”

Begonja AJ

Croatian Science Foundation and Croatian Academy of Arts and Sciences, Presentation of Tenure Track Pilot Program, Zagreb

11.05.2018.

Molekularni mehanizmi produkcije trombocita: uloga citoskeleta i fosfoinozitida.

Begonja AJ.

KroHem-Hrvatska kooperativna grupa za hematološke bolesti - proljetni sastanak, Vukovar

19.04.2018.

Molecular mechanisms governing platelet production: the role of PI3P and late endosomes/lysosomes

Begonja AJ.

Leibniz – Institut für Analytische Wissenschaften - ISAS, Dortmund, Njemačka

10.01.2018.

Greasing up megakaryocytes: the role of PI3P in platelet production.

Begonja AJ

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK

16.06.2017.

Platelet function, thrombopoiesis and immune thrombocytopenia.

Begonja AJ.

Ljetna škola “Javno zdravstvo i patofiziologija” Saint Cloud State Sveučilište/USA & Odjel za biotehnologiju/Sveučilište u Rijeci.

08.12.2016.

Akademska karijera: međunarodno i domaće iskustvo.

Begonja AJ.

Udruga studenata Biotehnologije, Odjel za biotehnologiju, Sveučilište u Rijeci

17.06.2016.

Platelet function, thrombopoiesis and immune thrombocytopenia.

Begonja AJ

Joint St. Cloud State University/USA & Department of Biotechnology/University of Rijeka Summer School “Public health and pathophysiology”. Rijeka, Croatia

17.12.2015.

Filamin A u regulaciji nastanka megakariocita.

Begonja AJ

HAZU 8. znanstvena tribina: biologija i patologija trombocita. Rijeka

17.11.2015.

From the biggest to the smallest: Filamin A regulates differentiation of megakaryocytes into platelets.

Antonija Jurak Begonja

International Centre for Genetic Engineering and Biotechnology (ICGEB). Trieste, Italy.

26.06.2015.

Platelet function, thrombopoiesis and immune thrombocytopenia.

Begonja AJ

Joint Saint Cloud State University/USA & Department of Biotechnology/University of Rijeka Summer School in Pathophysiology. Rijeka, Croatia

12.03.2015.

Molecular mechanisms of megakaryocyte and platelet development.

Begonja AJ.

Croatian Academy of Science and Arts Symposium: Developmental biology of platelets, thrombocitopenia, and myeloproliferative neoplasms. Rijeka, Croatia.

14.10.2014.

Sva lica trombocita.

Begonja AJ

3. Tribina Hrvatske akademije znanosti i umjetnosti: Novija postignuća u imunologiji i hematologiji, Rijeka

25.09.2014.

Filamin A stabilizes thrombopoietin receptor surface expression and inhibits its degradation

Begonja AJ, Grozovsky R, Hoffmeister KM, Falet H, Hartwig JH

2nd EUPLAN (European Platelet Network) Conference, Le Bischenberg, Francuska

09.12.2013.

The many faces of filamin A in megakaryocytes

Begonja AJ

Institute for clinical biochemistry and pathobiochemistry, Wurzburg, Germany

14.09.2013.

New Insights on Mechanisms of Platelet Production.

Begonja AJ

3rd Congress of Croatian Physiological Society and 1st Regional Congress of the Physiological Societies, Rijeka, Croatia

14.02.2013.

Razvojni put trombocita

Begonja AJ

Department of Biotechnology, University of Rijeka.

27.02.2012.

Filamin A and Thrombopoiesis.

Begonja AJ

Center for Thrombosis and Haemostasis, Mainz, Germany.

08.12.2008.

Differental role of cAMP and cGMP in megakaryocyte differentiation from mouse fetal liver stem cells.

Begonja AJ

Children’s Hospital Boston, USA.

18.04.2007.

Role of Cyclic Nucleotides in Development of Megakaryocytes.

Begonja AJ

Croatian Society of Medical Biochemists, Split, Croatia.

14.12.2006.

cGMP/cAMP Signaling in Megakaryocyte and Platelet Production.

Begonja AJ, Gambaryan S, Walter U.

SFB 688 Meeting, Wuerzburg, Germany.

21.09.2006.

Platelet Regulation by NAD(P)H Oxidase-Generated ROS and NO/cGMP Signaling.

Begonja AJ, Gambaryan S, Walter U.

Brigham and Women´s Hospital, Harvard Medical School, Boston, USA

14.12.2005.

Function of ROS in Platelets.

Begonja AJ, Gambaryan S, Walter U.

14th Virtual Platelet Meeting Club, Würzburg, Germany.

14.10.2005.

Differential Mechanisms of Platelet ROS Production by Thrombin and Convulxin.

Begonja AJ, Gambaryan S, Walter U.

XXth European Platelet Meeting, Ede, Netherlands. October 14th 2005.

16.07.1999.

Effect of Ochratoxin A on Cell Death and Intracellular ATP in Kidney RK-13 and LLC-PK1 Cells.

Begonja A, Bilopavlovic N, Petrik J, Barisic K, Juretic D.

Summer University of Biochemistry, Zadar, Croatia

19.05.2022. - 20.05.2022.

Vps34 kinase in megakaryocyte response to high platelet needs through interleukin-1-alpha. (Oral presentation)

Kolman R, Bertović I, Bruketa T, Bender M, Jurak Begonja A.

Oral presentation

1st Biomedicine and Health PhD Students Congress “Science and Us” Rijeka, Croatia

https://fdmri.uniri.hr/wp-content/uploads/2022/01/drugi-poziv_eng.pdf

28.04.2022. - 30.04.2022.

Phosphatidylinositol-4-kinase A inhibition leads to diminished integrin αIIbβ3 activation and impaired spreading of human platelets. (Oral presentation)

Čabrijan S, Bura A, Prtenjača N, Munitić I, Jurak Begonja A.

Oral presentation

10th Symposium on Hemostasis, Coagulation, Platelets and Transfusion Medicine Chapel Hill, North Carolina, USA, online presentation

https://www.med.unc.edu/bloodresearchcenter/event/10th-symposium-on-hemostasis/

01.12.2021. - 10.12.2021.

Vps34 localizes to the nucleolus and mediates early megakaryopoiesis.

Bertović I, Kolman R, Bruketa T, Begonja Jurak A.

Poster

ASCB-EMBO Cell Bio Virtual Online congress

17.07.2021. - 21.07.2021.

PI4P and PI(4,5)P2 immunofluorescence staining optimization in human platelets.

Bura A., Đurić I., Čabrijan S., Begonja AJ.

Poster

ISTH 2021: XXIX Congress of the international society on thrombosis and haemostasis Philadelphia, USA, online event.

17.07.2021. - 21.07.2021.

Early endosomal GTPase Rab5 regulates GPIb trafficking and platelet production in vitro.

Bertović I, Kurelić R, Mahmutefendić Lučin H, Begonja Jurak A.

Oral presentation. ISTH Fellowship I.B.

XXIX Congress of International Society of Thrombosis and Hemostasis (ISTH) Philadelphia, USA. Online meeting.

https://www.isth.org/default.aspx

03.07.2021. - 08.07.2021.

OCRL controls actin reorganization in spreading and activation of human platelets.

Bura A., Begonja A.J.

Poster and speed talk

The 45th FEBS Virtual Congress Molecules of Life: Towards New Horizons Ljubljana, Slovenia; online event.

03.07.2021. - 08.07.2021.

New potential role of Vps34 kinase in the control of the cell size.

Bertović I, Begonja Jurak A.

Poster

The 45th FEBS congress. Ljubljana, Slovenia. Online meeting.

https://2021.febscongress.org/

15.06.2021. - 18.6.2021.

New potential role of Vps34 kinase in the control of the cell size.

Bertović I, Begonja Jurak A. The 20th FEBS Young Scientists’ Forum (YSF).

Poster

The 20th FEBS Young Scientists’ Forum (YSF) Online meeting.

https://2021.febscongress.org/ysf-programme

29.3.2021. - 31.3.2021.

OCRL phosphatase controls actin reorganization during human and mouse platelet spreading.

Bura A., Staiano L., Morra V., De Matteis A.M., Jurak Begonja A.

Poster

2021 Platelet Society Meeting online

29.3.2021. - 31.3.2021.

Vps34 localizes to the nucleolus and mediates early megakaryopoiesis.

Bertović I., Jurak Begonja A.

Poster

2021 Platelet Society Meeting online

2.3.2021. - 3.3.2021.

OCRL phosphatase controls actin reorganization during the activation of human platelets spread on fibrinogen.

Bura A., Jurak Begonja A.

Poster

EMBO-EMBL Symposia, Life at the Periphery: Mechanobiology of the Cell Surface. online

https://www.embo-embl-symposia.org/symposia/2021/EES21-01/

2.12.2020. - 16.12.2020.

New potential role of the PI3KC3 in the nucleolus.

Bertović I, Jurak Begonja A.

Poster

Cell Bio Virtual 2020, ASCB-EMBO meeting. online

27.11.2020. - 28.11.2020.

OCRL phosphatase controls actin reorganization in human and mouse platelets spread on different matrices.

Bura A., Staiano L., Morra V., De Matteis A.M., Jurak Begonja A.

Poster

22. EMBL student congress: The Roaring 20s: A New Decade for Life Sciences; online

28.09.2019.

Role of PI3P in the remodeling of the intracellular compartments during MCMV infection.

Marcelic M, Mahmutefendic Lucin H, Jurak Begonja A, Blagojevic Zagorac G, Karleusa Lj, Jug Vucko N, Lukanovic Juric S, Pavisic V, Lucin P.

Poster

EMBO Workshop: Lipid function in heath and disease. Dresden, Germany

27.09.2019.

Early endosomal GTPase Rab5 mediates GPIb trafficking and platelet formation in vitro.

Bertović I, Kurelić R, Begonja Jurak A.

Poster, predavanje

HDBMB congress: Crossroads in Life Sciences. Lovran, Croatia

27.09.2019.

Characterization of Sorting nexin 9 (SNX9) in DAMI megakaryocytic cell line and primary mouse megakaryocytes.

Tomović E*, Bertović I*, Begonja Jurak A. *Autori su jednako kontribuirali.

Poster

HDBMB congress: Crossroads in Life Sciences. Lovran, Croatia

26.09.2019.

The role of PI(4,5)P2 and its phosphatase OCRL on actin cytoskeleton during platelet activation.

Bura A, Bertović I, Begonja Jurak A.

Poster - A.B. nagrada za najbolju postersku prezentaciju

HDBMB congress: Crossroads in Life Sciences. Lovran, Croatia

18.09.2019.

PI3P is involved in the remodeling of the membranous system during MCMV infection.

Marcelic M, Mahmutefendic Lucin H, Jurak Begonja A, Blagojevic Zagorac G, Karleusa Lj, Jug Vucko N, Lukanovic Juric S, Pavisic V, Lucin P.

Poster

13th Annual Meeting of Croatian Physiological Society with International Participation. Osijek, Croatia

12.09.2019.

The effect of Rac1 inhibitor EHT1864 on aggregation, spreading and GPVI clustering in human platelets.

Neagoe RAI, Stegner D, Jurak Begonja A, Nieswandt B, Watson SP, Poulter NS.

Poster

The 1st Platelet Society Meeting. Cambridge, UK

28.08.2019.

Early endosomal GTPase Rab5 regulates platelet production.

Bertović I, Kurelić R, Begonja Jurak A.

Poster, predavanje -I.B. nagrada za najbolju postersku prezentaciju

FEBS Advanced Course: Biochemistry of membrane proteins – Structure, Trafficking, Regulation. Budimpest, Hungary

14.06.2019.

The role of PI4P and its phosphatase SACM1L in primary megakaryocytes.

Bura A, Bertović I, Begonja Jurak A.

Poster

FEBS Advanced Course: Molecular Organization, Function and Dynamics of Biomembranes. Cargese, France

17.10.2018.

Expression and localization of SACM1L phosphatase and PI4P in Dami cell line and primary mouse megakaryocytes.

Bura A, Bertović I, Jurak Begonja A

Poster

The 2018 FEBS Special Meeting on Golgi: Membrane trafficking in cell organization and homeostasis. Sorrento, Italija

04.09.2018.

PI3P modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes

Bertović I, Kurelić R, Krauss M, Haucke V, Jurak Begonja A.

Poster

FEBS Advanced Course - Lipid dynamics and membrane contact sites. Spetses, Grčka

03.09.2018.

Characterization of SACM1L phosphatase and PI4P in Dami cell line and primary mouse megakaryocytes.

Bura A, Bertović I, Léon C, Jurak Begonja A.

Poster.

FEBS3+ konferencija "From Molecules to Living Systems" Siofok, Mađarska

15.06.2018.

PI3P modulates megakaryocyte maturation and proplatelet production in vitro.

Ivana Bertović, Roberta Kurelić, Michael Krauss, Volker Haucke, Antonija Jurak Begonja.

Poster

European Hematology Association (EHA) 23rd Congress Stockholm, Sweden

13.06.2018.

Several mechanisms contribute to photodynamic inhibition of HSV-1 infection.

Cokarić Brdovčak M, Djaković L, Bertović I, Lončarić M, Jurak Begonja A, Malatesti N, Jurak I.

Poster

31st International Conference on Antiviral Research (ICAR) Porto, Portugal

17.05.2018.

A novel cationic amphiphilic porphyrin-based photosensiter effectively inhibits replication of HSV-1 by several different mechanisms.

Cokaric Brdovčak M, Djaković L, Bertović I, Lončarić M, Jurak Begonja A, Malatesti N, Jurak I.

Poster

Power of Viruses, FEMS Poreč, Croatia

11.02.2018.

PI3P modulates megakaryocyte maturation and platelet production through late endosomes/lysosomes

Bertović I, Kurelić R, Krauss M, Haucke V, Jurak Begonja A

Talk, poster

Keystone Symposia: Phosphoinositide Biology: New Therapeutic Targets Beyond Class I PI3K Taos, NM, USA

22.09.2017.

Efficient photodynamic inhibition of hsv-1 replication using a novel cationic amphiphilic porphyrin.

Cokaric Brdovčak M, Djaković L, Bertović I, Knežević K, Jurak Begonja A, Malatesti N, Jurak I.

Poster

7. kongres slovenskog mikrobiološkog društva Bled, Slovenia

21.09.2017.

PI3P is important for early phase endosomal retention compartment (EPERC) formation in MCMV infected fibroblasts.

Marcelic M, Mahmutefendic H, Jurak Begonja A, Blagojevic Zagorac G, Karleusa Lj, Jug N, Lukanovic Juric S, Pavisic V, Lucin P.

Talk, poster

4th Congress of Croatian Physiological Society Dubrovnik, Croatia

07.09.2017.

Membrane traffic modulating lipid PI3P regulates platelet production.

Bertović I, Krauss M, Haucke V, Jurak Begonja A.

Talk - Award for the best oral presentation

1st Italian-UK Platelet Meeting Bath, UK

03.07.2017.

Membrane traffic modulating lipid PI3P regulates platelet production.

Bertović I, Krauss M, Haucke V, Jurak Begonja A.

Poster

2nd International Advances in Biomedical Research conference, MedILS Split, Croatia

14.06.2017.

Phosphatidylinositol 3-monophosphate (PI3P) regulates megakaryocyte maturation and proplatelet formation.

Bertović I, Krauss M, Haucke V, Jurak Begonja A.

Poster

FEBS/EMBO Advanced Lecture Course: Molecular Architecture, Dynamics and Function of Biomembranes Cargese, Korzika, Francuska

01.03.2017.

Differential levels and localization of PI3P in immature and mature megakaryocytes.

Bertović I, Krauss M, Haucke V, Jurak Begonja A.

Poster

Gordon Research Conference: Cell biology of megakaryocytes and platelets. Barga, Italy

22.09.2016.

Jurak Begonja A. Phosphatidylinositol 3-monophosphate (PI3P) regulates proplatelet formation in vitro.

Bertovic I, Banovic M, Paskvan P, Hartwig JH, Jurak Begonja A.

Poster- Award for the best poster presentation

3rd EUPLAN (European Platelet Network) Conference Bad Homburg, Germany

04.07.2016.

Phosphatidylinositol 3-monophosphate (PI3P) is required for platelet production in vitro.

Bertovic I, Jurak Begonja A.

Poster

Croatian Academy of Sciences and Arts 14th Symposium: Translation of basic immunology and neuroscience tools to therapies; Rijeka, Croatia

01.09.2015.

Expression of PI3P binding phox (PX) domain inhibits megakaryocyte development into proplatelets.

Bertovic I, Banovic M, Hartwig JH, Jurak Begonja A.

Poster

Biochemical Society UK & FEBS, Signalling 2015: Cellular Functions of Phosphoinositides and Inositol Phosphates Cambridge, UK

20.06.2015.

Beta galactosyltransferase (B4GALT1) is a key reggulator of hematopoetic stem cell function and thrombopoiesis.

Giannini S, Adelman M, Jurak Begonja A, Hoffmeister KM.

Oral

International Society of Thrombosis and Hemostasis Congress (ISTH) Toronto, Canada

20.04.2015.

Beta 1,4 Galactosyltransferase 1 is a key regulator of hematopoietic stem cell function and thrombopoiesis.

Giannini S, Adelman M, Begonja AJ, Mullally A, Hoffmeister KM.

Poster

Gordon Research Conference: Cell Biology of Megakaryocytes & Platelets Barga, Italija

06.12.2014.

The F-BAR Protein PACSIN2 Regulates Platelet Intracellular Membrane Architecture and in Vivo Hemostatic Functions

Jönsson T, Pluthero F, Begonja AJ, Kormann J, Demers M, Wagner DD, Plomann M, Hartwig JH, Kahr WH, Falet H

Poster

56th American Society of Hematology Meeting San Francisco, CA, SAD

06.12.2014.

Posttranslational Modification in Megakaryocytes Regulates ß1 Integrin Expression, Migration and Platelet Production in Vivo

Giannini S, Adelman M, Begonja AJ, Hoffmeister KM

Poster

56th American Society of Hematology Meeting San Francisco, CA, SAD

06.12.2014.

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro.

Grozovsky R, Begonja AJ, Hartwig JH, Falet H, Hoffmeister KM

Plenarno predavanje

56th American Society of Hematology Meeting San Francisco, CA, SAD

05.12.2013.

Aberrant Type-2-Lactosaminoglycan Synthesis Severely Impairs Thrombopoiesis

Giannini S, Jurak Begonja A, Adelmann M, Hoffmeister KM.

Poster

55th American Society of Hematology Annual Meeting and Exposition New Orleans, LA, USA

29.06.2013.

The hepatic Ashwell-Morell receptor regulates thrombopoietin production.

Hoffmeister KM, Grozovsky R, Begonja AJ, Hartwig JH.

Talk

International Society on Thrombosis and Haemostasis XXIV Congress Amsterdam, Netherlands

10.03.2013.

Correct LacNAc synthesis is required for platelet production.

Giannini S, Adelman M, Begonja AJ, Hoffmeister KM.

Poster

Gordon Research Conference Galveston, TX, USA

10.03.2013.

The F-BAR protein PACSIN 2 orchestrates the intracellular membrane architecture of platelets and megakaryocytes.

Jönsson T, Begonja AJ, Bender M, Kim H, Kormann J, Merkl B, Pluthero F, Kahr WH, Hartwig JH, Plomann M, Falet H.

Poster

Gordon Research Conference Galveston, TX, USA

10.03.2013.

Filamin A regulates thrombopoietin c-Mpl receptor function.

Begonja AJ, Grozovsky R, Hoffmeister KM, Falet H, Hartwig JH.

Poster

Gordon Research Conference Galveston, TX, USA

05.12.2012.

Clearance of Desialylated Platelets by the Hepatic Asialoglycoprotein Receptor Regulates TPO Homeostasis in Vivo

Grozovsky, Renata; Begonja, Antonija Jurak; Hartwig, John H; Hoffmeister, Karin M;

Poster

54th American Society of Hematology Meeting Atlanta, USA

09.12.2011.

The F-BAR Protein PACSIN 2 Specifically Coats the Anastomosing Intracellular Membrane Systems of Platelets and Megakaryocytes

Jonsson, Terese; Begonja, Antonija Jurak; Kormann, Jan; Merkl, Barbara; Pluthero, Fred; Kahr, Walter H; Hartwig, John H; Plomann, Markus; Falet, Herve

Poster

53rd American Society of Hematology Meeting San Diego, USA

09.12.2011.

Size Limits the Ability of Platelets to Undergo Abcission

Thon JN, Macleod H, Begonja AJ, Zhu J, Lee KC, Mogilner A, Hartwig JH, Italiano JE.

Online publication

53rd American Society of Hematology Meeting San Diego, USA

09.12.2011.

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

Begonja, Antonija Jurak; Nguyen, Lilly; Italiano Jr, Joseph E; Falet, Herve; Meiri, Karina F; Hartwig, John H;

Poster

53rd American Society of Hematology Meeting San Diego, USA

09.12.2011.

ß-1,4-Galactosyltransferase 1 Expression Is Required for Platelet Production in Vitro and In Vivo.

Giannini S, Grozovsky R, Begonja AJ, Hoffmeister KM.

Talk

53rd American Society of Hematology Meeting San Diego, USA

09.11.2011.

. ß-1,4-Galactosyltransferase 1 Expression Is Required for Platelet Production in Vitro and In Vivo.

Giannini S, Grozovsky R, Begonja AJ, Hoffmeister KM.

Poster

Annual Conference of the Society for Glycobiology Seattle, USA

23.07.2011.

Expression and localization of the membrane-binding and -deforming protein, pacsin 2, in platelets and megakaryocytes.

Jönsson T, Begonja AJ, Hartwig JH, Falet H.

Poster

International Society on Thrombosis and Haemostasis XXIII Congress Kyoto, Japan

20.03.2011.

Expression and localization of the membrane-binding and -deforming protein, pacsin 2, in platelets and megakaryocytes.

Jönsson T, Begonja AJ, Hartwig JH, Falet H.

Poster

Gordon Research Conference Galveston, TX, USA

20.03.2011.

FlnA null megakaryocytes prematurely release large and fragile platelets that spontaneously microvesiculate and poorly circulate.

Begonja AJ, Hoffmeister K, Hartwig JH, Falet H.

Gordon Research Conference Galveston, TX, USA

04.12.2010.

Filamin A Deficiency Leads to Premature Platelet Formation and Increased Clearance

Begonja, Antonija Jurak; Weber, Sarah E; Hoffmeister, Karin M; Hartwig, John H; Falet, Herve;

Poster

52nd American Society of Hematology Meeting Orlando, USA

11.07.2009.

Megakaryocytes and Thrombopoiesis.

Hartwig JH, Begonja A, Falet H, Patel-Hett S, Thon J, Italiano J.

Talk

International Society on Thrombosis and Haemostasis XXII Congress Boston, MA, USA

11.07.2009.

Differential Roles of cAMP and cGMP in Megakaryocyte Maturation and Platelet Formation.

Begonja AJ, Gambaryan S, Schulze H, Patel-Hett S, Italiano Jr. JE, Hartwig J, Walter U.

Poster

International Society on Thrombosis and Haemostasis XXII Congress Boston, MA, USA

05.03.2005.

Platelet NAD(P)H Oxidase-Mediated ROS Production Regulates alphaIIb beta3 Activation.

Begonja AJ, Gambaryan S, Geiger J, Walter U.

Poster

Gordon Research Conference Buellton, CA, USA

2004.

Endothelin (1-21) levels in various degrees of alcoholic liver cirrhosis

Antoljak, Nataša; Peran, Nena; Vrkić, Nada; Begonja, Antonija; Duvnjak, Marko; Topić, Elizabeta;

2003.

Plasma Levels of Soluble Adhesion Molecules sICAM-1 in Atherosclerosis Related Diseases

Vrkić, Nada; Šimundić, Ana-Maria; Begonja, Antonija; Topić, Elizabeta; Nikolić Heitzler, Vjeran; Bulj, Nikola; Babić, Zdravko; Manola, Šime; Pintarić, Hrvoje; Žarković, Neven

Poster

11th ALPE ADRIA CARDIOLOGY MEETING

2003.

MTHFR polymorphism in patients with head and neck cancer

Begonja, Antonija; Topić, Elizabeta; Štefanović, Mario; Šimundić, Ana-Maria;

2003.

Cytochrome P450-CYP2C9 Genotyping in Warfarin Drug Therapy Optimization

Štefanović, Mario; Topić, Elizabeta; Samardžija, Marina; Šimundić, Ana-Maria; Begonja, Antonija;

2003.

PAI-1 and fibrinogen polymorphisms in patients with myocardial infarction in Croatia

Begonja, Antonija; Topić, Elizabeta; Šimundić, Ana-Maria; Štefanović, Mario; Nikolić, Vjeran

Poster

EUROMEDLAB 2003, IFCC Congress of Clinical Chemistry Barcelona

2003.

Razine endotelina (1-21) u različitim stupnjevima alkoholne ciroze jetre( Endothelin (1-21) levels in various degress of alcoholic liver cirrhossis )

Antoljak, Nataša; Peran, Nena; Vrkić, Nada; Begonja, Antonija; Topić, Elizabeta; Duvnjak, Marko

Poster

4. hrvatski kongres medicinskih biokemičara Zagreb

2003.

ENDOTELIN I ČINITELJ RASTA JETRE U BOLESNIKA S KORONARNOM BOLESTI SRCA( ENDOTHELIN AND HEPATOCYTE GROWTH FACTOR IN PATIENTS WITH CORONARY ARTERY DISEASE )

Antoljak, Nataša; Vrkić, Nada; Begonja, Antonija; Nikolić-Heitzler, Vjeran; Bulj, Nikola

4. hrvatski kongres medicinskih biokemičara Zagreb

2003.

Polimorfizam metilentetrahidrofolat reduktaze kao čimbenik rizika za rak glave i vrata( Methylenetetrahydrofolate reductase polymorphism and risk of head and neck cancer )

Begonja, Antonija; Topić, Elizabeta; Štefanović, Mario; Šimundić, Ana-Maria

4. hrvatski kongres medicinskih biokemičara Zagreb

2002.

CYP2D6 polymorphism in patients with head and neck cancer

Štefanovic, Mario; Begonja, Antonija; Topić, Elizabeta; Čurčić, Ivica; Šimundić, Ana-Maria;

2002.

PCR-RFLP genotyping of two beta-fibrinogen gene polymorphisms

Begonja, Antonija; Topić, Elizabeta; Šimundić, Ana-Maria; Štefanović, Mario;

2002.

Plasma levels of vasoactive propeptides (proANP and BigET-1) in patients with acute myocardial infarction treated by percutaneous coronary intervention

Vrkić, Nada; Nikolić-Heitzler, Vjeran; Begonja, Antonija; Antoljak, Nataša; Topić, Elizabeta;

2002.

Association of warfarin dosing with cytochrome P450-CYP2C9 genetic polymorphism

Štefanović, Mario; Topić, Elizabeta; Samardžija, Marina; Begonja, Antonija;

2002.

Plasma levels of vasoactive peptides (proANP and BigET-1) and solubile adhesion molecules (sICAM-1) in patients with acute myocardial infarction (AMI) treated by percutaneous coronary intervention (PCI)

Vrkić, Nada; Nikolić-Heitzler, Vjeran; Žarković, Neven; Begonja, Antonija; Topić, Elizabeta

Poster

18th International congress of clinical chemistry and laboratory medicine (ICCC)

2002.

ProANP (1-98), but not cystatin C has predictive value for occurance of acute renal insufficiency in critically ill septic patients

Vrkić, Nada; Mazul Sunko, Branka; Antoljak, Nataša; Krizmanić-Dekanić, Ankica; Begonja, Antonija; Tešija, Andrea; Topić, Elizabeta

Poster

7th Alps-Adria Congress Regensburg

2002.

Cytochrome P450 - CYP2D6 polymorphism in head and neck cancer patients

Štefanovic, Mario; Begonja, Antonija; Topić, Elizabeta; Čurčić, Ivica; Šimundic, Ana-Maria

Poster

European Human Genetics Conference 2002 Strasbourg

2002.

Genetic polymorphism of Cytochrome P450 CYP2D6 and CYP2C9 enzymes among Croatian population

Štefanović, Mario; Topić, Elizabeta; Samardžija, Marina; Begonja, Antonija

Poster

13th Congress of the European Anthropological Association Zagreb

2002.

Plasminogen activator inhibitor-1 4G5G polymorphism in stroke patients

Begonja, Antonija; Topić, Elizabeta; Šimundić, Ana-Maria; Štefanović, Mario

Poster

European Human Genetics Conference 2002 Strasbourg

2002.

Plasminogen activator inhibitor-1 genotype distribution in stroke patients

Begonja, Antonija; Topić, Elizabeta; Šimundić, Ana-Maria; Štefanović, Mario

Poster

7th Alps-Adria Congress Regensburg

2002.

Polymorphisms of some coagulation factor genes in healthy Croatian subjects

Begonja, Antonija; Topić, Elizabeta; Šimundić, Ana-Maria; Štefanović, Mario

13th Congress of the European Anthropological Association Zagreb

2001.

A new factor V Leiden PCR-SSCP detection method

Šimundić, Ana-Maria; Štefanović, Mario; Begonja, Antonija; Topić, Elizabeta;

2001.

A new genotyping method for PAI-1 4G/5G polymorphism

Begonja, Antonija; Šimundić, Ana-Maria; Štefanović, Mario; Topić, Elizabeta;

2001.

Genetska varijacija faktora V, faktora II i inhibitora plazminogen aktivatora-1 u bolesnika s cerebrovaskularnim inzultom (Genetic variation of factor V, factor II and inhibitor of plasminogen activator-1 in stroke patients)

Begonja, Antonija; Topić, Elizabeta; Šimundić, Ana-Maria; Štefanović, Mario

Hrvatski kongres medicinskih biokemičara

1999.

Učinak okratoksina-A na apoptozu, nekrozu i razinu staničnog ATP-a u RK13 i LLC-PK1 bubrežnim stanicama( Effect of ochratoxin-A on apoptosis, necrosis and cellular ATP level in RK13 and LLC-PK1 renal cells )

Petrik, Jozsef; Koszegi, Tamas; Begonja, Antonija; Bilopavlović, Nada; Juretić, Dubravka; Kellermayer, Miklos; Čepelak, Ivana; Žanić Grubišić, Tihana; Pepeljnjak, Stjepan

Treći hrvatski kongres medicinskih biokemičara Zagreb

Polymorphism of CYP2C9 and CYP2D6 in Predicting Drug Metabolism Phenotype

Topić, Elizabeta; Štefanović, Mario; Čulav, Jadranka; Samardžija, Marina; Blazinić, Franciska; Begonja, Antonija

Predicting the Warfarin Therapy Dose by Cytochrome P450-CYP2C9 Genotyping

Štefanović, Mario; Topić, Elizabeta; Samardžija, Marina; Begonja, Antonija;

Association of UDP Glucuronosyl Transferase Genetic Polymorphism with Gilbert Syndrome among Croatian Children

Topić, Elizabeta; Štefanović, Mario; Begonja, Antonija; Žaja Franulović, Orjena; Jurčić, Zvonko;

NAD(P)H Oxidase Modulates GPIIbIIIa Activity In Platelets.

Begonja AJ, Gambaryan S, Geiger J, Aktas B, Walter U.

Poster

XIXth European Platelet Meeting Bad Brueckenau, Germany

MTHFR polymorphism in patients with cerebrovascular insult and deep venous thrombosis

Topić, Elizabeta; Turek-Čubrilo, Mirjana; Begonja, Antonija; Šimundić, Ana-Maria; Demarin, Vida; Stančić, Vladimir; Žuntar, Irena

1.2021. -

N/A

Robert Kolman Doktorat

Medicinska kemija

Odjel za biotehnologiju, Sveučilište u Rijeci

1.2021. -

N/A

Sara Čabrijan Doktorat

Medicinska kemija

Odjel za biotehnologiju, Sveučilište u Rijeci

10.2018. - 12.2022.

The role of PI(4,5)P2 and PI4P in megakaryocyte maturation, proplatelet formation, and platelet function

Ana Bura Doktorat

Medicinska kemija

Odjel za biotehnologiju, Sveučilište u Rijeci

Datum obrane: 20.12.2022.

01.04.2015. - 22.03.2021.

The role of Vps34 and phosphatidylinositol 3-monophosphate (PI3P) in megakaryocyte maturation and platelet production

Ivana Bertović Doktorat

Medicinska kemija

Odjel za biotehnologiju, Sveučilište u Rijeci

Datum obrane: 22.03.2021.

28.09.2022. - 30.09.2022.

Croatian Society of Biochemistry and Molecular Biology HDBMB22: FROM SCIENCE TO KNOWLEDGE

Brela, Croatia član znanstvenog odbora

25.09.2019. - 28.09.2019.

Kongres Hrvatskog društva za biokemiju i molekularnu biologiju "Crossroads in Life Sciences"

Lovran, Hrvatska član organizacijskog odbora

03.03.2017. - 26.02.2017.

Gordon Research Conference “Cell Biology of Megakaryocytes and Platelets”

Barga, Italy Invited Discussion Leader

2015. -

Croatian Academy of Sceince and Arts Symposium: Developmental biology of platelets, thrombocitopenia, and myeloproliferative neoplasms.

Rijeka, Croatia. Scientific board, member.

2021.

IJMS

2020.

Hämostaseologie

2020.

Platelets

2019.

Blood

2017.

Periodicum biologorum

2016.

Cell Communication and Signaling

2015.

Thrombosis Research

2021. - 2023.

“Zakrpa intervertebralnog diska - (IVD zakrpa) rješava križobolju”, koordinator dr. Zlatko Kolić, Poliklinika Medico

suradnik

Hamag Bicro - Povećanje razvoja novih proizvoda i usluga koji proizlaze iz aktivnosti istraživanja i razvoja

30.12.2020. - 30.12.2024.

Projekt razvoja karijera mladih istraživača - izobrazba novih doktora znanosti

voditelj, mentor

HRZZ

01.07.2019. - 30.06.2022.

Nucleolar control of megakaryopoiesis

voditelj

American Society of Hematology (ASH) Global Research Award $150.000,00

01.10.2018. - 30.09.2022.

Projekt razvoja karijera mladih istraživača - izobrazba novih doktora znanosti

voditelj, mentor

HRZZ

01.09.2018. - 31.08.2022.

ITN- Marie Curie "Targeting Platelet Adhesion Receptors in Thrombosis"

suradnik

Horizon 2020

15.09.2016. - 14.09.2019.

HRZZ Uspostavni istraživački projekt #2400 "Ulogoga fosfoinozitida u nastanku trombocita"

voditelj

HRZZ

01.09.2016. - 01.09.2020.

Projekt razvoja karijera mladih istraživača - izobrazba novih doktora znanosti

voditelj, mentor

HRZZ

2016. - 31.12.2018.

ICGEB Research Grant - CRP Collaborative Research Programme - Early Career Return Grant "Deciphering the role of phosphoinositol lipids in thrombopoiesis"

voditelj

ICGEB

01.09.2014. - 31.08.2016.

The role of PI3P in thrombopoiesis

Voditelj

NEWFELPRO Marie Curie-FP7-COFUND

2014. -

Uloga fosfatidilinozitida u nastanku trombocita

Voditelj projekta

Sveučilište u Rijeci 48000.00 HRK

2011. - 2013.

Mechanisms of thrombocytopenia in WASP and WIP null mice

Član tima, post-doc

NIH RO1

2007. - 2011.

Filamin A-Syk interactions modulate platelet ITAM-based signaling

Član tima, post-doc

NIH RO1

2004. - 2007.

Cardiovascular cell-cell interactions

Član tima, doktorand

DFG/SFB 688

2014-2020

Europski socijalni fond (ESF) Učinkoviti ljudski potencijali (2014. - 2020.), Internacionalizacija visokog obrazovanja UP.03.1.1.02.0019 Strateška internacionalizacija diplomskih studija matematike i biotehnologije - OPTILIFE. Suradnik.

Financiranje: Europski socijalni fond (ESF), 1.799.346,08 kn