dr. sc. Ilija Brizić mag. ing. biotechn.

Medicinski fakultet Centar za proteomiku
Medicinski fakultet Centar za proteomiku

MEĐUNARODNA VIDLJIVOST:
CITATIH-INDEXI10-INDEX
Google scholar 123 6 5
ORCID
ResearcherID 76 5

Članstva

1.1.2015. - Society for Natural Immunity
1.1.2014. - Povjerenstvo za dobrobit životinja, Medicinski fakultet Rijeka
1.1.2013. - Hrvatsko imunološko društvo
- CROLASA Hrvatsko društvo za znanost o laboratorijskim životinjama

Znanstvena i umjetnička djelatnost

Znanstveni radovi

1. Hiršl, Lea; Brizić, Ilija; Jenuš, Tina; Lisnić, Vanda Juranić; Reichel, Johanna Julia; Jurković, Slaven; Krmpotić, Astrid; Jonjić, Stipan;
Murine cMV expressing the high affinity nKg2D ligand MUlT-1: a Model for the Development of cytomegalovirus-Based Vaccines
Frontiers in immunology 9 - 2018.

Q1

2. Šestan, Marko; Marinović, Sonja; Kavazović, Inga; Cekinović, Đurđica; Wueest, Stephan; Wensveen, Tamara Turk; Brizić, Ilija; Jonjić, Stipan; Konrad, Daniel; Wensveen, Felix M;
Virus-induced interferon-? causes insulin resistance in skeletal muscle and derails glycemic control in obesity
Immunity 49 164-177. e6 - 2018.

Q1
WOS
Exc

3. Brizić, Ilija; Lisnić, Berislav; Brune, Wolfram; Hengel, Hartmut; Jonjić, Stipan;
Cytomegalovirus Infection: Mouse Model
Current protocols in immunology 122 e51 - 2018.

Q1
WOS

4. Zaytseva, Olga O; Jansen, Bas C; Hanić, Maja; Mrčela, Mia; Razdorov, Genadij; Stojković, Ranko; Erhardt, Julija; Brizić, Ilija; Jonjić, Stipan; Pezer, Marija;
MIgGGly (mouse IgG glycosylation analysis)-a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS
Scientific reports 8 13688 - 2018.

Q1
WOS

5. Brizić, Ilija; Sušak, Božo; Arapović, Maja; Huszthy, Peter C; Hiršl, Lea; Kveštak, Daria; Lisnić, Vanda Juranić; Golemac, Mijo; Pugel, Ester Pernjak; Tomac, Jelena;
Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation
European journal of immunology - 2018.

Q1
WOS

6. Wu, Yiquan; Prager, Adrian; Boos, Simone; Resch, Moritz; Brizic, Ilija; Mach, Michael; Wildner, Sabrina; Scrivano, Laura; Adler, Barbara;
Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-? as a key for entry
PLoS pathogens 13 e1006281 - 2017.

Q1
WOS
Exc

7. Hirche, Christoph; Frenz, Theresa; Haas, Simon F; Döring, Marius; Borst, Katharina; Tegtmeyer, Pia-K; Brizic, Ilija; Jordan, Stefan; Keyser, Kirsten; Chhatbar, Chintan;
Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo
Cell reports 19 2345-2356 - 2017.

Q1
WOS
Exc

8. Miletic, Antonija; Lenartic, Maja; Popovic, Branka; Brizic, Ilija; Trsan, Tihana; Miklic, Karmela; Mandelboim, Ofer; Krmpotic, Astrid; Jonjic, Stipan;
NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation
European journal of immunology - 2017.

Q1
WOS

9. Brizić, Ilija; Hiršl, Lea; Britt, William J; Krmpotić, Astrid; Jonjić, Stipan;
Immune responses to congenital cytomegalovirus infection
Microbes and infection - 2017.

Q2
WOS

10. Arapović, Maja; Brizić, Ilija; Popović, Branka; Jurković, Slaven; Jordan, Stefan; Krmpotić, Astrid; Arapović, Jurica; Jonjić, Stipan;
intrinsic contribution of Perforin to nK-cell homeostasis during Mouse cytomegalovirus infection
Frontiers in immunology 7 133 - 2016.

Q1
WOS

11. Sampaio, Kerstin Laib; Stegmann, Cora; Brizic, Ilija; Adler, Barbara; Stanton, Richard J; Sinzger, Christian;
The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression
Journal of General Virology 97 1917-1927 - 2016.

Q2

12. Rovis, Tihana Lenac; Brlic, Paola Kucan; Kaynan, Noa; Lisnic, Vanda Juranic; Brizic, Ilija; Jordan, Stefan; Tomic, Adriana; Kvestak, Daria; Babic, Marina; Tsukerman, Pinchas;
Inflammatory monocytes and NK cells play a crucial role in DNAM-1–dependent control of cytomegalovirus infection
Journal of Experimental Medicine 213 1835-1850 - 2016.

Q1
WOS
Exc

13. Lemmermann, Niels AW; Krmpotic, Astrid; Podlech, Jürgen; Brizic, Ilija; Prager, Adrian; Adler, Heiko; Karbach, Astrid; Wu, Yiquan; Jonjic, Stipan; Reddehase, Matthias J;
Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread
PLoS pathogens 11 e1004640 - 2015.

Q1
WOS
Exc

14. Brizić, Ilija; Roviš, Tihana Lenac; Krmpotić, Astrid; Jonjić, Stipan;
MCMV avoidance of recognition and control by NK cells
Seminars in immunopathology 36 641-650 - 2014.

Q1
WOS

15. Wagner, Felicia M; Brizic, Ilija; Prager, Adrian; Trsan, Tihana; Arapovic, Maja; Lemmermann, Niels AW; Podlech, Jürgen; Reddehase, Matthias J; Lemnitzer, Frederic; Bosse, Jens Bernhard;
The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex
PLoS pathogens 9 e1003493 - 2013.

Q1
WOS
Exc

Pozvana predavanja

1. Ilija Brizić
Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation
Poreč - 17.5.2018.
2. Brizić Ilija
Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation
Zagreb - Godišnji kongres Hrvatskog imunološkog društva HID2017 - 21.10.2017.

Kongresna priopćenja

1.
Brizić I., Lesac A., Lisnić B., Juranić Lisnić V., Gotovac K., Borovečki F., Krmpotić A., Jonjić S.
Dramatic changes in NK cell phenotype and function following perinatal MCMV infection Poster prezentacija 3rd international symposium of the virtual institute VISTRIE Braunschweig (Germany) - 22.5.2015.
2.
Brizić I., Lesac A., Juranić Lisnić V., Lisnić B., Krmpotić A., Jonjić S.
Dramatic changes in NK cell phenotype and function following perinatal MCMV infection Poster prezentacija 1st Croatian virus workshop Rijeka (Croatia) - 14.11.2014.
3.
Felicia M. Wagner, Ilija Brizic, Adrian Prager, Frederic Lemnitzer, Jens Bernhard Bosse, Martina Gimpfl, Lisa Marcinowski, Margaret MacDonald, Heiko Adler, Ulrich H. Koszinowski and Barbara Adler
The Viral Chemokine MCK-2 of Murine Cytomegalovirus Promotes Infection as Part of a gH/gL/MCK-2 Complex Usmeno izlaganje Annual Meeting of Croatian Immunological Society Marija Bistrica
4.
Brizić I., Lesac A., Juranić Lisnić V., Lisnić B., Krmpotić A., Jonjić S.
Dramatic changes in NK cell phenotype and function following perinatal MCMV infection Poster prezentacija 2nd Waldthausen Castle Symposium (Margaret Gladys Smith 60th anniversary of Cytomegalovirus isolation) Budenheim (Germany)
5.
Zaitseva, Olga; Jansen, Bas; Hanić, Maja; Mrčela, Mia; Razdorov, Genadij; Erhardt, Julija; Brizić, Ilija; Jonjić, Stipan; Pezer, Marija; Lauc, Gordan;
Analysis of Fc-linked N-glycosylation of mouse IgG with nanoUPLC-ESI-MS
6.
Zaitseva, Olga; Jansen, Bas; Hanić, Maja; Mrčela, Mia; Razdorov, Genadij; Erhardt, Julija; Brizić, Ilija; Jonjić, Stipan; Pezer, Marija; Lauc, Gordan;
Analysis of Fc-linked N-glycosylation of mouse IgG with nanoUPLC-ESI-MS
7.
Tegtmeyer, Pia-katharina; Spanier, Julia; Borst, Katharina; Doering, Marius; Hirche, Christoph; Lienenklaus, Stefan; Brizic, Ilija; Jonjic, Stipan; Kalinke, Ulrich;
spatiotemporal analysis of the contribution of different recognition platforms to mouse cytomegalovirus-induced type I interferon: Mo-p1-4
8.
Kveštak, Daria; Brizić, Ilija; Arapović, Jurica; Arapović, Maja; Huszthy, Peter Csaba; Šušak, Božo; Golemac, Mijo; Pugel, Ester Pernjak; Torti, Nicole; Oxenius, Annette;
Perinatal mouse cytomegalovirus infection induces activation of brain resident microglial cells and recruitment of inflammatory cells into the brain
9.
Sestan, M; Valentic, S; Reichel, JJ; Brizic, I; Jonjic, S; Wensveen, FM; Polic, B;
Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity
10.
Kveštak, Daria; Brizić, Ilija; Arapović, Jurica; Arapović, Maja; Huszthy, Peter Csaba; Šušak, Božo; Golemac, Mijo; Pugel, Ester Pernjak; Torti, Nicole; Oxenius, Annette;
Perinatal mouse cytomegalovirus infection induces activation of brain resident microglial cells and recruitment of inflammatory cells into the brain
11.
Sestan, M; Valentic, S; Reichel, JJ; Brizic, I; Jonjic, S; Wensveen, FM; Polic, B;
Cytomegalovirus infection enhances development of glucose intolerance and insulin resistance in obesity
12.
Tegtmeyer, Pia-Katharina; Spanier, Julia; Doering, Marius; Hirche, Christoph; Lienenklaus, Stefan; Brizic, Ilija; Jonjic, Stipan; Kalinke, Ulrich;
ID: 218: Murine cytomegalovirus triggers interferon-ß in a TLR-, RLH-, and STING-dependent manner, whereas only TLR/RLH-dependent signaling is needed for survival
13.
Hirche, Christoph; Frenz, Theresa; Haas, Simon; Brizic, Ilija; Keyser, Kirsten; Döring, Marius; Halle, Stephan; Förster, Reinhold; Jonjic, Stipan; Messerle, Martin;
Virus infections differentially modulate the cell cycle state and functionality of dormant long-term hematopoietic stem cells in vivo
14.
Roviš, Tihana Lenac; Kučan, Paola; Kaynan, Noa; Lisnić, Vanda Juranić; Brizić, Ilija; Jordan, Stefan; Tomić, Adriana; Babić, Marina; Tsukerman, Pinchas; Colonna, Marco;
Viral downregulation of CD155 reveals strong effect of DNAM-1 in virus control by NK cells and macrophages
15.
Jonjić, Stipan; Roviš, Tihana Lenac; Kučan, Paola; Brizić, Ilija; Stanietsky, Noa; Lisnić, Vanda Juranić; Jordan, Stefan; Tomić, Adriana; Babić, Marina; Tsukerman, Pinchas;
''Cytomegalovirus downregulation of PVR reveals strong effect of DNAM-1 in virus control by NK cells and macrophages''
16.
Hirche, Christoph; Frenz, Theresa; Haas, Simon; Brizic, Ilija; Keyser, Kirsten; Döring, Marius; Halle, Stephan; Förster, Reinhold; Jonjic, Stipan; Messerle, Martin;
Virus infections differentially modulate the cell cycle state and functionality of dormant long-term hematopoietic stem cells in vivo
17.
Tegtmeyer, Pia-Katharina; Spanier, Julia; Doering, Marius; Hirche, Christoph; Lienenklaus, Stefan; Brizic, Ilija; Jonjic, Stipan; Kalinke, Ulrich;
ID: 218: Murine cytomegalovirus triggers interferon-ß in a TLR-, RLH-, and STING-dependent manner, whereas only TLR/RLH-dependent signaling is needed for survival
18.
Roviš, Tihana Lenac; Kučan, Paola; Kaynan, Noa; Lisnić, Vanda Juranić; Brizić, Ilija; Jordan, Stefan; Tomić, Adriana; Babić, Marina; Tsukerman, Pinchas; Colonna, Marco;
Viral downregulation of CD155 reveals strong effect of DNAM-1 in virus control by NK cells and macrophages
19.
Jonjić, Stipan; Roviš, Tihana Lenac; Kučan, Paola; Brizić, Ilija; Stanietsky, Noa; Lisnić, Vanda Juranić; Jordan, Stefan; Tomić, Adriana; Babić, Marina; Tsukerman, Pinchas;
''Cytomegalovirus downregulation of PVR reveals strong effect of DNAM-1 in virus control by NK cells and macrophages''
20.
Grabušić, Kristina; Lisnić, Vanda Juranić; Popović, Branka; Kučić, Natalia; Brizić, Ilija; Jonjić, Stipan; Lučin, Pero;
EXTRACELLULAR ENRICHMENT OF SPECIFIC NONVIRION MCMV PROTEINS
21.
Grabušić, Kristina; Lisnić, Vanda Juranić; Popović, Branka; Kučić, Natalia; Brizić, Ilija; Jonjić, Stipan; Lučin, Pero;
EXTRACELLULAR ENRICHMENT OF SPECIFIC NONVIRION MCMV PROTEINS
22.
Brizić I., Lesac A., Juranić Lisnić V., Lisnić B., Krmpotić A., Jonjić S.
Dramatic changes in NK cell phenotype and function following perinatal MCMV infection Oralna prezentacija Annual meeting of the croatian immunological society Krk (Croatia)
23.
Felicia M. Wagner, Ilija Brizic, Adrian Prager, Tihana Trsan, Maja Arapovic, Niels A. W. Lemmermann, Jurgen Podlech, Matthias J. Reddehase, Frederic Lemnitzer, Jens Bernhard Bosse, Martina Gimpfl, Lisa Marcinowski, Margaret MacDonald, Heiko Adler, Ulrich H. Koszinowski, Barbara Adler
The Viral Chemokine MCK-2 of Murine Cytomegalovirus Promotes Infection as Part of a gH/gL/MCK-2 Complex Poster 2nd Meeting of Middle-European Societies for Immunology and Allergology Opatija
24.
Brizić I., Lesac A., Juranić Lisnić V., Lisnić B., Krmpotić A., Jonjić S.
Dramatic changes in NK cell phenotype and function following perinatal MCMV infection Poster prezentacija 15th meeting of the Society for Natural Immunity Montebello (Canada)

Znanstveni projekti

1. 1.10.2017. - 30.9.2022.
Jačanje kapaciteta CerVirVac-a za istraživanja u virusnoj imunologiji i vakcinologiji; suradnik; Europski fond za regionalni razvoj (EFRR); HRK 37.716.072,15; http://zci-cervirvac.hr/hr/projekti/efrr/
2. 1.7.2014. - 30.6.2018.
Aktivacijski receptori NK-stanica specificni za virus i njihovo izbjegavanje od strane virusa; suradnik; Hrvatska zaklada za znanost; 991.460,00 HRK; http://capri.com.hr/virus-specific-activating-nk-cell-receptors-and-their-viral-immunoevasion.html
3. 1.11.2013. - 31.10.2017.
Methods for high-throughput glycoproteomic analysis (HTP-GlycoMet); suradnik; FP7 program Marie Curie Actions - Industry-Academia Partnerships and Pathways; EUR 1.818.077,09; http://capri.com.hr/methods-for-high-throughput-glycoproteomic-analysis-fp7-marie-curie-actions-iapp.html
4. 1.1.2013. - 1.1.2018.
Strengthening adaptive immunity via innate immunity: enhancing the CD8 T cell response by using the NKG2D ligand expressed in a herpesvirus vector (StAdvInn); Suradnik; FP7 - European Research Council (ERC) Advanced Grant; ;
5. 1.1.2013. - 1.1.2016.
'Platform for trans-Academic Cooperation in Innovation (PACINNO); Suradnik; IPA Adriatic Cross Border Cooperation 2007-2013; ;
6. 1.1.2013. -
Night-of-the-Lab-Out; Suradnik; Europska komisija, FP7 Marie-Curie Action; ;
7. 20.12.2012. - 1.12.2013.
Novi snažni CMV-promotor za proizvodnju proteina i molekula RNK; Suradnik; BICRO; 401.180,00; http://www.bicro.hr/index.php/poc-financirani/poc-4-krug#24-sveučilište-u-rijeci-medicinski-fakultet-novi-snažni-cmv-promotor-za-proizvodnju-proteina-i-nekodirajućih-molekula-rna
8. 1.1.2012. - 1.1.2013.
Upgrading the capacities for research in translational medicine at the Faculty of Medicine University of Rijeka" (TransMedRi); Suradnik; EU FP7; ;
9. 1.1.2011. - 1.1.2016.
Viral Strategies of Immune Evasion" (VISTRIE); Suradnik; Helmholtz Association; ;
10. 1.1.2010. - 1.1.2011.
The development of a model for immunotherapy of viral infections by using recombinant proteins, which connect the innate and specific immune responses; Suradnik; NZZ; ;
11. -
Uloga NK stanica u patogenezi kongenitalne infekcije citomegalovirusom; Voditelj projekta; Hrvatska zaklada za znanost; ;

Mentorstvo doktorandima

1. 1.10.2014. -
Božo Sušak; Doktorat Uloga tkivno-rezidentnih limfocita T u mozgu nakon prirođene citomegalovirusne infekcije; Biomedicina i zdravstvo; ;

Znanstveni skupovi

1. 28.5.2018. - 1.6.2018.
The 17th Meeting of the Society for Natural Immunity San Antonio (SAD) sudionik
2. 16.5.2018. - 18.10.2018.
Power of viruses Poreč (Hrvatska) Pozvano predavanje
3. 20.10.2017. - 21.10.2017.
2017 ANNUAL MEETING OF THE CROATIAN IMMUNOLOGICAL SOCIETY Zagreb Pozvano predavanje
4. 14.10.2016. - 15.10.2016.
Annual Meeting of the Croatian Immunological Society Ogulin (Croatia) Sudionik
5. 2.10.2016. - 5.10.2016.
16th Meeting of the Society for the Natural Immunity Taormina (Italy) Sudionik
6. 23.7.2016. - 27.7.2016.
41st Annual International Herpesvirus Workshop (IHW2016 Madison (USA) Sudionik
7. 22.5.2015. -
3rd international symposium of the virtual institute VISTRIE Braunschweig (Germany) Sudionik
8. 2.5.2015. - 6.5.2015.
15th meeting of the Society for natural immunity Montebello (Canada) Sudionik
9. 21.11.2014. - 22.11.2014.
2nd Waldthausen castle symposium (Margaret Gladys Smith: 60th anniversary of cytomegalovirus isolation) Budenheim (Germany) Sudionik
10. 14.11.2014. -
1st Croatian virus workshop Rijeka (Croatia) Sudionik
11. 17.10.2014. - 18.10.2014.
Annual meeting of the Croatian immunological society Krk (Croatia) Sudionik
12. 10.10.2013. - 13.10.2013.
2nd Meeting of Middle-European Societies for Immunology and Allergology Opatija Sudionik
13. 5.10.2012. - 6.10.2012.
Annual Meeting of Croatian Immunological Society Marija Bistrica Sudionik

Stručna djelatnost